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  • cancer clinical trials in knoxville, TN

  • S0722: Everolimus in Treating Patients With Pleural Malignant Mesothelioma That Cannot Be Removed By Surgery
    U.T. Medical Center Cancer Institute
    Knoxville, Tennessee 37920-6999
    Malignant Mesothelioma
    Neuropsychological and Behavioral Testing in Young Patients With Cancer
    East Tennessee Childrens Hospital
    Knoxville, Tennessee 37916
    Chemotherapeutic Agent Toxicity, Cognitive/Functional Effects, Neurotoxicity, Psychosocial Effects of Cancer and Its Treatment, Radiation Toxicity, Unspecified Childhood Solid Tumor, Protocol Specific
    Paclitaxel, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, or Ixabepilone With or Without Bevacizumab in Treating Patients With Stage IIIC or Stage IV Breast Cancer
    Thompson Cancer Survival Center

    Trial Locations
    Thompson Cancer Survival Center
    University of Tennessee - Knoxville
    Male Breast Cancer, Recurrent Breast Cancer, Stage IIIC Breast Cancer, Stage IV Breast Cancer
    Topotecan With or Without Aflibercept in Treating Patients With Extensive-Stage Small Cell Lung Cancer
    University of Tennessee - Knoxville
    Knoxville, Tennessee 37920
    Extensive Stage Small Cell Lung Cancer, Recurrent Small Cell Lung Cancer
    Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors
    East Tennessee Childrens Hospital
    Knoxville, Tennessee 37916
    Adult Rhabdomyosarcoma, Adult Synovial Sarcoma, Childhood Hepatoblastoma, Childhood Synovial Sarcoma, Previously Treated Childhood Rhabdomyosarcoma, Recurrent Adrenocortical Carcinoma, Recurrent Adult Soft Tissue Sarcoma, Recurrent Childhood Liver Cancer, Recurrent Childhood Rhabdomyosarcoma, Recurrent Childhood Soft Tissue Sarcoma, Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, Recurrent Neuroblastoma, Recurrent Osteosarcoma, Recurrent Retinoblastoma, Recurrent Wilms Tumor and Other Childhood Kidney Tumors
    Sorafenib and Erlotinib in Treating Patients With Pancreatic Cancer That Cannot Be Removed by Surgery
    Baptist Regional Cancer Center at Baptist Riverside
    Knoxville, Tennessee 37901
    Pancreatic Cancer
    NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer
    Center for Biomedical Research - Oncology
    Knoxville, Tennessee 37909
    Colorectal Cancer
    Paclitaxel With or Without Carboplatin and/or Bevacizumab Followed By Doxorubicin and Cyclophosphamide in Treating Patients With Breast Cancer That Can Be Removed by Surgery
    Thompson Cancer Survival Center
    Knoxville, Tennessee 37916
    Estrogen Receptor-negative Breast Cancer, HER2-negative Breast Cancer, Male Breast Cancer, Progesterone Receptor-negative Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Triple-negative Breast Cancer
    Zoledronic Acid in Treating Patients With Metastatic Breast Cancer, Metastatic Prostate Cancer, or Multiple Myeloma With Bone Involvement
    Thompson Cancer Survival Center
    Knoxville, Tennessee 37916
    Breast Cancer, Metastatic Cancer, Multiple Myeloma and Plasma Cell Neoplasm, Musculoskeletal Complications, Pain, Prostate Cancer, Urinary Complications
    S0904: Docetaxel With or Without Vandetanib in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
    U.T. Medical Center Cancer Institute
    Knoxville, Tennessee 37920-6999
    Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer
    Temozolomide and Radiation Therapy With or Without Bevacizumab in Treating Patients With Newly Diagnosed Glioblastoma
    Thompson Cancer Survival Center
    Knoxville, Tennessee 37916
    Adult Giant Cell Glioblastoma, Adult Glioblastoma, Adult Gliosarcoma
    Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer
    East Tennessee Children's Hospital
    Knoxville, Tennessee 37901
    Leukemia, Neoplasm of Uncertain Malignant Potential, Unspecified Childhood Solid Tumor, Protocol Specific
    Study of Kidney Tumors in Young Patients
    East Tennessee Children's Hospital
    Knoxville, Tennessee 37901
    Kidney Cancer, Nonneoplastic Condition
    Collecting and Storing Tissue From Young Patients With Cancer
    East Tennessee Children's Hospital
    Knoxville, Tennessee 37901
    Cancer
    Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma
    East Tennessee Children's Hospital
    Knoxville, Tennessee 37901
    Sarcoma
    Collecting and Storing Biological Samples From Patients With Ewing Sarcoma
    East Tennessee Children's Hospital
    Knoxville, Tennessee 37901
    Sarcoma
    Collecting and Storing Biological Samples From Young Patients With Hodgkin's Lymphoma
    East Tennessee Children's Hospital
    Knoxville, Tennessee 37901
    Lymphoma
    Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma
    East Tennessee Children's Hospital
    Knoxville, Tennessee 37901
    Neuroblastoma
    Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma
    East Tennessee Childrens Hospital
    Knoxville, Tennessee 37916
    Adult Rhabdomyosarcoma, Childhood Desmoplastic Small Round Cell Tumor, Chordoma, Desmoid Tumor, Metastatic Childhood Soft Tissue Sarcoma, Nonmetastatic Childhood Soft Tissue Sarcoma, Previously Treated Childhood Rhabdomyosarcoma, Previously Untreated Childhood Rhabdomyosarcoma, Recurrent Adult Soft Tissue Sarcoma, Recurrent Childhood Rhabdomyosarcoma, Recurrent Childhood Soft Tissue Sarcoma, Stage I Adult Soft Tissue Sarcoma, Stage II Adult Soft Tissue Sarcoma, Stage III Adult Soft Tissue Sarcoma, Stage IV Adult Soft Tissue Sarcoma
    Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors
    East Tennessee Children's Hospital
    Knoxville, Tennessee 37901
    Brain and Central Nervous System Tumors
    S9925: Collecting and Storing Samples From Patients With Lung Cancer
    Thompson Cancer Survival Center
    Knoxville, Tennessee 37916
    Lung Cancer
    An Extension Protocol for Multiple Sclerosis Patients Who Participated in Genzyme-Sponsored Studies of Alemtuzumab
    Hope Neurology
    Knoxville, Tennessee
    Multiple Sclerosis, Relapsing-Remitting
    Radiation Therapy With or Without Androgen-Deprivation Therapy in Treating Patients With Prostate Cancer
    Thompson Cancer Survival Center
    Knoxville, Tennessee 37916
    Prostate Cancer
    Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor
    East Tennessee Childrens Hospital
    Knoxville, Tennessee 37916
    Diffuse Hyperplastic Perilobar Nephroblastomatosis, Rhabdoid Tumor of the Kidney, Stage I Wilms Tumor, Stage II Wilms Tumor, Stage III Wilms Tumor, Stage IV Wilms Tumor, Stage V Wilms Tumor
    S0819: Carboplatin/Paclitaxel With or Without Bevacizumab and/or Cetuximab in Stage IV or Recurrent Non-Small Cell Lung Cancer
    Thompson Cancer Survival Center

    Trial Locations
    Thompson Cancer Survival Center
    U.T. Medical Center Cancer Institute
    Lung Cancer
    Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer
    U.T. Medical Center Cancer Institute
    Knoxville, Tennessee 37920-6999
    Chemotherapeutic Agent Toxicity, Fallopian Tube Cancer, Neurotoxicity, Ovarian Cancer, Pain, Peripheral Neuropathy, Primary Peritoneal Cavity Cancer
    Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Liver Cancer
    East Tennessee Childrens Hospital
    Knoxville, Tennessee 37916
    Childhood Hepatoblastoma, Stage I Childhood Liver Cancer, Stage II Childhood Liver Cancer, Stage III Childhood Liver Cancer, Stage IV Childhood Liver Cancer
    Bendamustine as Second-Line Therapy in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer
    Baptist Regional Cancer Center at Baptist Riverside
    Knoxville, Tennessee 37901
    Lung Cancer
    Collecting and Storing Tissue Samples From Patients With Rare or Cutaneous Non-Hodgkin Lymphoma
    East Tennessee Children's Hospital
    Knoxville, Tennessee 37901
    Lymphoma, Lymphoproliferative Disorder
    Rituximab and Alemtuzumab in Treating Older Patients With Progressive Chronic Lymphocytic Leukemia
    U.T. Medical Center Cancer Institute
    Knoxville, Tennessee 37920-6999
    Leukemia
    Sorafenib Tosylate With or Without Doxorubicin Hydrochloride in Treating Patients With Locally Advanced or Metastatic Liver Cancer
    University of Tennessee - Knoxville
    Knoxville, Tennessee 37920
    Adult Primary Hepatocellular Carcinoma, Advanced Adult Primary Liver Cancer, Localized Unresectable Adult Primary Liver Cancer, Recurrent Adult Primary Liver Cancer
    Combination Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin Lymphoma
    East Tennessee Childrens Hospital
    Knoxville, Tennessee 37916
    Childhood Nodular Lymphocyte Predominant Hodgkin Lymphoma, Stage III Childhood Hodgkin Lymphoma, Stage IV Childhood Hodgkin Lymphoma
    Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma
    East Tennessee Childrens Hospital
    Knoxville, Tennessee 37916
    Adult Rhabdomyosarcoma, Alveolar Childhood Rhabdomyosarcoma, Embryonal Childhood Rhabdomyosarcoma, Metastatic Childhood Soft Tissue Sarcoma, Previously Untreated Childhood Rhabdomyosarcoma, Stage IV Adult Soft Tissue Sarcoma
    Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Younger Patients With Newly Diagnosed Ependymoma
    East Tennessee Childrens Hospital
    Knoxville, Tennessee 37916
    Childhood Infratentorial Ependymoma, Childhood Supratentorial Ependymoma, Newly Diagnosed Childhood Ependymoma
    A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer
    University of Tennessee - Knoxville
    Knoxville, Tennessee 37920
    Breast Cancer
    Stem Cell Transplant With Lenalidomide Maintenance in Patients With Multiple Myeloma (BMT CTN 0702)
    Thompson Cancer Survival Center
    Knoxville, Tennessee 37916
    Multiple Myeloma
    Everolimus in Treating Patients With Kidney Cancer Who Have Undergone Surgery
    U.T. Medical Center Cancer Institute
    Knoxville, Tennessee 37920-6999
    Kidney Cancer
    Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Stage IV Melanoma
    Thompson Cancer Survival Center
    Knoxville, Tennessee 37916
    Acral Lentiginous Malignant Melanoma, Lentigo Maligna Malignant Melanoma, Nodular Malignant Melanoma, Recurrent Melanoma, Solar Radiation-related Skin Melanoma, Stage IV Melanoma, Superficial Spreading Malignant Melanoma
    Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
    East Tennessee Children's Hospital
    Knoxville, Tennessee 37901
    Leukemia
    Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery
    Thompson Cancer Survival Center

    Trial Locations
    Thompson Cancer Survival Center
    U.T. Medical Center Cancer Institute
    Colorectal Cancer
    Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia
    East Tennessee Childrens Hospital
    Knoxville, Tennessee 37916
    Childhood Hepatoblastoma, Previously Treated Childhood Rhabdomyosarcoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Malignant Germ Cell Tumor, Recurrent Childhood Rhabdomyosarcoma, Recurrent Childhood Soft Tissue Sarcoma, Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, Recurrent Neuroblastoma, Recurrent Osteosarcoma, Recurrent Wilms Tumor and Other Childhood Kidney Tumors
    Study of Paclitaxel/Carboplatin With or Without Bavituximab in Previously Untreated Non Small-Cell Lung Cancer
    Hematology-Oncology of Knoxville/Mercy Medical Center
    Knoxville, Tennessee 37909
    Non-Squamous Non-Small Cell Lung Cancer
    Paclitaxel and Carboplatin With or Without Bevacizumab in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer
    University of Tennessee - Knoxville
    Knoxville, Tennessee 37920
    Brenner Tumor, Ovarian Clear Cell Cystadenocarcinoma, Ovarian Endometrioid Adenocarcinoma, Ovarian Mixed Epithelial Carcinoma, Ovarian Mucinous Cystadenocarcinoma, Ovarian Serous Cystadenocarcinoma, Ovarian Undifferentiated Adenocarcinoma, Stage IIA Fallopian Tube Cancer, Stage IIA Ovarian Epithelial Cancer, Stage IIA Primary Peritoneal Cavity Cancer, Stage IIB Fallopian Tube Cancer, Stage IIB Ovarian Epithelial Cancer, Stage IIB Primary Peritoneal Cavity Cancer, Stage IIC Fallopian Tube Cancer, Stage IIC Ovarian Epithelial Cancer, Stage IIC Primary Peritoneal Cavity Cancer, Stage IIIA Fallopian Tube Cancer, Stage IIIA Ovarian Epithelial Cancer, Stage IIIA Primary Peritoneal Cavity Cancer, Stage IIIB Fallopian Tube Cancer, Stage IIIB Ovarian Epithelial Cancer, Stage IIIB Primary Peritoneal Cavity Cancer, Stage IIIC Fallopian Tube Cancer, Stage IIIC Ovarian Epithelial Cancer, Stage IIIC Primary Peritoneal Cavity Cancer, Stage IV Fallopian Tube Cancer, Stage IV Ovarian Epithelial Cancer, Stage IV Primary Peritoneal Cavity Cancer
    Lenalidomide or Observation in Treating Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma
    University of Tennessee - Knoxville
    Knoxville, Tennessee 37920
    Light Chain Deposition Disease, Smoldering Multiple Myeloma
    Risk-Adapted Chemotherapy in Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia
    East Tennessee Childrens Hospital
    Knoxville, Tennessee 37916
    B-cell Childhood Acute Lymphoblastic Leukemia, Philadelphia Chromosome Positive Childhood Precursor Acute Lymphoblastic Leukemia, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Childhood Acute Lymphoblastic Leukemia
    Everolimus With or Without Bevacizumab in Treating Patients With Advanced Kidney Cancer That Progressed After First-Line Therapy
    Thompson Cancer Survival Center

    Trial Locations
    Thompson Cancer Survival Center
    University of Tennessee - Knoxville
    Clear Cell Renal Cell Carcinoma, Recurrent Renal Cell Cancer, Stage III Renal Cell Cancer, Stage IV Renal Cell Cancer
    Everolimus and Octreotide With or Without Bevacizumab in Treating Patients With Locally Advanced or Metastatic Pancreatic Neuroendocrine Tumors That Cannot Be Removed By Surgery
    Thompson Cancer Survival Center

    Trial Locations
    Thompson Cancer Survival Center
    University of Tennessee - Knoxville
    Gastrinoma, Glucagonoma, Insulinoma, Pancreatic Alpha Cell Adenoma, Pancreatic Alpha Cell Carcinoma, Pancreatic Beta Islet Cell Adenoma, Pancreatic Beta Islet Cell Carcinoma, Pancreatic Delta Cell Adenoma, Pancreatic Delta Cell Carcinoma, Pancreatic G-cell Adenoma, Pancreatic G-cell Carcinoma, Pancreatic Polypeptide Tumor, Recurrent Islet Cell Carcinoma, Recurrent Pancreatic Cancer, Somatostatinoma, Stage III Pancreatic Cancer, Stage IV Pancreatic Cancer
    Studying First Line Treatment of Chronic Myeloid Leukemia (CML) in a Real-world Setting
    Thompson Cancer Survival Center

    Trial Locations
    Thompson Cancer Survival Center
    Tennessee Cancer Specialists
    University of Tennessee Medical Center
    Chronic Myeloid Leukemia
    Chemotherapy With or Without Trastuzumab After Surgery in Treating Women With Invasive Breast Cancer
    Thompson Cancer Survival Center
    Knoxville, Tennessee 37916
    Estrogen Receptor-negative Breast Cancer, Estrogen Receptor-positive Breast Cancer, HER2-positive Breast Cancer, Progesterone Receptor-negative Breast Cancer, Progesterone Receptor-positive Breast Cancer, Recurrent Breast Cancer, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIC Breast Cancer