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  • cancer clinical trials in durham, NC

  • Investigation of Genetic Determinants of Capecitabine Toxicity
    Duke University
    Durham, North Carolina 27710
    Breast Cancer
    Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer
    Duke University Medical Center
    Durham, North Carolina 27710
    Endometrial Adenocarcinoma, Endometrial Adenosquamous Cell Carcinoma, Endometrial Clear Cell Carcinoma, Recurrent Endometrial Carcinoma, Stage III Endometrial Carcinoma, Stage IV Endometrial Carcinoma
    Epigenetic Modulation in Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
    Duke University Medical Center
    Durham, North Carolina 27710
    Diffuse Large B-cell Lymphoma
    Impact of Aggressive Versus Standard Drainage Regimen Using a Long Term Indwelling Pleural Catheter
    Duke University Medical Center
    Durham, North Carolina 27710
    Pleural Effusion, Malignant
    Pharmacokinetics (PK) Study of AC480 for Recurrent Glioma
    The Preston Robert Tisch Brain Tumor Center at Duke University Medical Center
    Durham, North Carolina 27710
    Glioma
    Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Liver Cancer
    Duke University Medical Center
    Durham, North Carolina 27710
    Childhood Hepatoblastoma, Stage I Childhood Liver Cancer, Stage II Childhood Liver Cancer, Stage III Childhood Liver Cancer, Stage IV Childhood Liver Cancer
    Red Cell Storage Duration Study
    Duke University
    Durham, North Carolina 27710
    Cardiac Surgery, Erythrocyte Transfusion
    IMGN901 in Combination With Lenalidomide and Dexamethasone
    Duke University Medical Center
    Durham, North Carolina 27710
    Multiple Myeloma
    The FIRSTT: Comparing MRgFUS(MR-guided Focused Ultrasound) Versus UAE (Uterine Artery Embolization)for Uterine Fibroids.
    Duke University Health System
    Durham, North Carolina 27705
    Symptomatic Uterine Leiomyomas, Fibroids, Uterine Fibroids, Myomas
    Extension Study of Lapatinib Plus Herceptin With or Without Endocrine Therapy
    Duke University
    Durham, North Carolina 27710
    Breast Cancer
    Collecting and Storing Tissue Samples From Patients With Rare or Cutaneous Non-Hodgkin Lymphoma
    Duke Cancer Institute
    Durham, North Carolina 27710
    Lymphoma, Lymphoproliferative Disorder
    Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastoma
    The Preston Robert Tisch Brain Tumor Center at Duke
    Durham, North Carolina 27710
    Malignant Glioma, Glioblastoma Multiforme, Gliosarcoma
    Reduced Intensity Transplant Conditioning Regimen for Severe Thalassemia
    Duke University
    Durham, North Carolina 27710
    Severe Thalassemia
    Study Evaluating Two Dose Levels of Targretin Capsules in Patients With Refractory Cutaneous T-cell Lymphoma (CTCL)
    Duke University
    Durham, North Carolina 27710
    Refractory Cutaneous T-cell Lymphoma
    Daily Everolimus in Combination With Trastuzumab and Vinorelbine in HER2/Neu Positive Women With Locally Advanced or Metastatic Breast Cancer
    Duke University Medical Center Dept. of DUMC (2)
    Durham, North Carolina 27710
    HER2/Neu Over-expressing Locally Advanced Breast Cancer, Metastatic Breast Cancer
    Gemcitabine Hydrochloride and Docetaxel With or Without Bevacizumab in Treating Patients With Advanced or Recurrent Uterine Leiomyosarcoma
    Duke University Medical Center
    Durham, North Carolina 27710
    Recurrent Uterine Sarcoma, Stage IIIA Uterine Sarcoma, Stage IIIB Uterine Sarcoma, Stage IIIC Uterine Sarcoma, Stage IVA Uterine Sarcoma, Stage IVB Uterine Sarcoma, Uterine Leiomyosarcoma
    Moderate to Persistent Asthma in the Obese Subject
    Duke Asthma Allergy and Airway Center
    Durham, North Carolina 27704
    Asthma
    N2007-03: Vorinostat and 131-I MIBG in Treating Patients With Resistant or Relapsed Neuroblastoma
    Duke University Medical Center
    Durham, North Carolina 27710
    Neuroblastoma
    Panobinostat or Placebo With Bortezomib and Dexamethasone in Patients With Relapsed Multiple Myeloma
    Duke University Medical Center
    Durham, North Carolina 27710
    Multiple Myeloma
    Ofatumumab, Pentostatin, and Cyclophosphamide in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
    Duke University Medical Center
    Durham, North Carolina 27710
    Hematopoietic/Lymphoid Cancer, B-cell Chronic Lymphocytic Leukemia, Contiguous Stage II Small Lymphocytic Lymphoma, Noncontiguous Stage II Small Lymphocytic Lymphoma, Stage 0 Chronic Lymphocytic Leukemia, Stage I Chronic Lymphocytic Leukemia, Stage I Small Lymphocytic Lymphoma, Stage II Chronic Lymphocytic Leukemia, Stage III Chronic Lymphocytic Leukemia, Stage III Small Lymphocytic Lymphoma, Stage IV Chronic Lymphocytic Leukemia, Stage IV Small Lymphocytic Lymphoma
    Combination Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin Lymphoma
    Duke University Medical Center
    Durham, North Carolina 27710
    Childhood Nodular Lymphocyte Predominant Hodgkin Lymphoma, Stage III Childhood Hodgkin Lymphoma, Stage IV Childhood Hodgkin Lymphoma
    AMG 102 in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
    Duke Comprehensive Cancer Center
    Durham, North Carolina 27710
    Fallopian Tube Cancer, Ovarian Cancer, Malignant Tumor of Peritoneum
    Phase 2A Study of NPC-1C Chimeric Monoclonal Antibody to Treat Pancreatic and Colorectal Cancer
    Duke University Medical Center
    Durham, North Carolina 27710
    Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer
    Teen CHAT: Improving Physician Communication With Adolescents About Healthy Weight
    Duke University Medical Center - Cancer Prevention, Detection and Control
    Durham, North Carolina 27710
    Communication, Obesity, Nutrition, Physical Activity, Sleep
    Preoperative Radiation Therapy for High Risk Prostate Cancer
    Duke University Medical Center
    Durham, North Carolina 27710
    Prostate Cancer
    Monoclonal Antibody Ch14.18, Sargramostim, Aldesleukin, and Isotretinoin After Autologous Stem Cell Transplant in Treating Patients With Neuroblastoma
    Duke University Medical Center
    Durham, North Carolina 27710
    Disseminated Neuroblastoma, Localized Resectable Neuroblastoma, Localized Unresectable Neuroblastoma, Regional Neuroblastoma, Stage 4S Neuroblastoma
    Gemcitabine Hydrochloride or Pemetrexed Disodium and Carboplatin With or Without Celecoxib in Treating Patients With Advanced Non-Small Cell Lung Cancer
    Veterans Affairs Medical Center - Durham

    Trial Locations
    Veterans Affairs Medical Center - Durham
    Duke Cancer Institute
    Lung Cancer
    Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma
    Duke University Medical Center
    Durham, North Carolina 27710
    Adult Rhabdomyosarcoma, Alveolar Childhood Rhabdomyosarcoma, Embryonal Childhood Rhabdomyosarcoma, Metastatic Childhood Soft Tissue Sarcoma, Previously Untreated Childhood Rhabdomyosarcoma, Stage IV Adult Soft Tissue Sarcoma
    Safety and Efficacy of TKI258 in Relapsed or Refractory Multiple Myeloma Patients, Who Are With or Without t(4;14) Chromosomal Translocation
    Duke University Medical Center Dept. of DUMC (4)
    Durham, North Carolina 27710
    Relapsed or Refractory Multiple Myeloma
    A Trial of AMG 479, Everolimus (RAD001) and Panitumumab in Patients With Advanced Cancer
    Duke University Medical Center
    Durham, North Carolina 27710
    Advanced Solid Tumors
    Exercise and Lung Cancer Trial
    Duke University Medical Center
    Durham, North Carolina 27710
    Lung Cancer
    Ovarian Cancer Vaccine for Patients in Remission
    Duke University Medical Center
    Durham, North Carolina 27710
    Epithelial Ovarian Cancer
    Immunotherapy Study for Surgically Resected Pancreatic Cancer
    Duke University Medical Center
    Durham, North Carolina 27710
    Pancreatic Cancer
    Dose Escalation Study of Safety and Tolerability of AT-406 in Patients With Advanced Solid Tumors and Lymphomas
    Duke University Medical Center
    Durham, North Carolina 27710
    Cancer, Solid Tumors, Lymphoma, Malignancy
    Changes in Brain Function in Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Who Are Receiving Chemotherapy
    Duke Cancer Institute
    Durham, North Carolina 27710
    Cognitive/Functional Effects, Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer
    Connect® MM- The Multiple Myeloma Disease Registry
    DUMC Division of Cellular Therapy/ABMT
    Durham, North Carolina 27705
    Multiple Myeloma
    Carboplatin and Paclitaxel or Oxaliplatin and Capecitabine, With or Without Bevacizumab, as First-Line Therapy in Treating Patients With Newly Diagnosed Stage II, Stage III, Stage IV, or Recurrent Stage I Epithelial Ovarian Cancer or Fallopian Tube Cancer
    Duke University Medical Center
    Durham, North Carolina 27710
    Ovarian Mucinous Cystadenocarcinoma, Ovarian Mucinous Cystadenoma With Proliferating Activity, Recurrent Fallopian Tube Cancer, Recurrent Ovarian Epithelial Cancer, Stage IA Fallopian Tube Cancer, Stage IA Ovarian Epithelial Cancer, Stage IB Fallopian Tube Cancer, Stage IB Ovarian Epithelial Cancer, Stage IC Fallopian Tube Cancer, Stage IC Ovarian Epithelial Cancer, Stage IIA Fallopian Tube Cancer, Stage IIA Ovarian Epithelial Cancer, Stage IIB Fallopian Tube Cancer, Stage IIB Ovarian Epithelial Cancer, Stage IIC Fallopian Tube Cancer, Stage IIC Ovarian Epithelial Cancer, Stage IIIA Fallopian Tube Cancer, Stage IIIA Ovarian Epithelial Cancer, Stage IIIB Fallopian Tube Cancer, Stage IIIB Ovarian Epithelial Cancer, Stage IIIC Fallopian Tube Cancer, Stage IIIC Ovarian Epithelial Cancer, Stage IV Fallopian Tube Cancer, Stage IV Ovarian Epithelial Cancer
    Efficacy of Panobinostat in Patients With Relapsed and Bortezomib-refractory Multiple Myeloma
    Duke University Medical Center Dept. of DUMC (4)
    Durham, North Carolina 27710
    Relapsed and Bortezomib Refractory Multiple Myeloma, Refractory Multiple Myeloma, Relapsed Multiple Myeloma
    Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
    Duke University Medical Center
    Durham, North Carolina 27710
    Childhood Low-grade Cerebellar Astrocytoma, Childhood Low-grade Cerebral Astrocytoma, Childhood Mixed Glioma, Recurrent Childhood Brain Stem Glioma, Recurrent Childhood Cerebellar Astrocytoma, Recurrent Childhood Cerebral Astrocytoma, Recurrent Childhood Oligodendroglioma, Recurrent Childhood Visual Pathway and Hypothalamic Glioma, Recurrent Childhood Visual Pathway Glioma
    A Phase I Safety Study of a Cancer Vaccine to Treat HLA-A2 Positive Advanced Stage Ovarian, Breast and Prostate Cancer
    Duke University Medical Center
    Durham, North Carolina 27710
    Ovarian Neoplasms, Breast Neoplasms, Prostatic Neoplasms
    Study in Head and Neck Cancer
    For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    Durham, North Carolina
    Head and Neck Neoplasms
    Chronic Graft-versus-Host Disease Treatment (BMT CTN 0801)
    Duke University Medical Center
    Durham, North Carolina 27710
    Chronic GVHD
    Phase II Study of Afinitor vs. Sutent in Patients With Metastatic Non-Clear Cell Renal Cell Carcinoma
    Duke Univeristy Medical Center
    Durham, North Carolina 27710
    Advanced Non-clear Cell Renal Cell Carcinoma
    Stem Cell Transplant With Lenalidomide Maintenance in Patients With Multiple Myeloma (BMT CTN 0702)
    Duke University Medical Center
    Durham, North Carolina 27710
    Multiple Myeloma
    AMG 102 and Avastin for Recurrent Malignant Glioma
    The Preston Robert Tisch Brain Tumor Center
    Durham, North Carolina 27710
    Glioblastoma Multiforme, Gliosarcoma
    Study of GMI-1070 for the Treatment of Sickle Cell Pain Crisis
    Duke University Medical Center
    Durham, North Carolina 27710
    Sickle Cell Disease, Vaso-occlusive Crisis, Pain Crisis
    Epigenetic Modulation in Relapsed/Refractory Follicular Lymphoma and Marginal Zone Lymphoma
    Duke University Medical Center
    Durham, North Carolina 27710
    Follicular Lymphoma, Marginal Zone Lymphoma
    Evaluating the Safety and Tolerability of the Poly-ADP Ribose (PARP) Inhibitor With FOLFIRI in Subjects With Solid Tumor
    Site Reference ID/Investigator# 24922
    Durham, North Carolina 27710
    Gastric Cancer
    Study of AR-67 in Adult Patients With Recurrence of Glioblastoma Multiforme (GBM) or Gliosarcoma
    Duke University Medical Center - The Preston Robert Tisch Brain Tumor Center
    Durham, North Carolina 27710
    Glioblastoma Multiforme, GBM, Gliosarcoma
    A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB
    Duke University Medical Center Duke - Baker
    Durham, North Carolina 27710
    Medulloblastoma,, Rhabdomyosarcoma,, Neuroblastoma,, Hepatoblastoma,, High Grade Glioma,, Astrocytoma
    Safety and Efficacy of BKM120 in Combination With Trastuzumab in Patients With Relapsing HER2 Overexpressing Breast Cancer Who Have Previously Failed Trastuzumab
    Duke University Medical Center Duke South 2
    Durham, North Carolina 27710
    Metastatic Breast Cancer, Trastuzumab, BKM120, HER2+
    Cediranib Maleate in Treating Patients With Recurrent or Persistent Endometrial Cancer
    Duke University Medical Center
    Durham, North Carolina 27710
    Endometrial Adenocarcinoma, Endometrial Adenosquamous Cell Carcinoma, Endometrial Clear Cell Carcinoma, Endometrial Papillary Serous Carcinoma, Recurrent Endometrial Carcinoma
    Specimen Collection for Agricultural Health Study Cohort Pesticide Exposure Study
    Battelle
    Durham, North Carolina
    Multiple Myeloma, Leukemia, MGUS, MBL
    A Multicenter, Open-label Study of CMX001 Treatment of Serious Diseases or Conditions Caused by dsDNA Viruses
    Duke University Medical Center
    Durham, North Carolina 27710
    Male or Female Patients With a Serious or Immediately Life-threatening, Disease or Condition Caused by CMV, ADV, HSV, VAVC, VARV or, Monkeypox Viruses(s) Who Have a Life Expectancy of ≥ 2 Weeks and for, Whom no Comparable or Satisfactory Alternative Therapy is Available
    Study of Elacytarabine Versus Investigator's Choice in Patients With Late Stage Acute Myeloid Leukaemia (AML)
    Duke University Medical Center
    Durham, North Carolina 27710
    Acute Myeloid Leukemia (AML)
    Extension Study to Evaluate the Long-term Efficacy and Safety of Everolimus in Liver Transplant Recipients
    Duke University Medical Center
    Durham, North Carolina 27710
    Liver Transplant Recipient
    Bioavailability and Food Effect Study of TKI258 (CSF Capsule vs. FMI Tablet) in Adult Patients With Advanced Solid Tumors
    Novartis Investigative Site
    Durham, North Carolina 27710
    Neoplasm, Cancer, Tumors
    Paclitaxel and Carboplatin With or Without Bevacizumab in Treating Patients With Stage II, Stage III, or Stage IV Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer
    Duke University Medical Center
    Durham, North Carolina 27710
    Brenner Tumor, Ovarian Clear Cell Cystadenocarcinoma, Ovarian Endometrioid Adenocarcinoma, Ovarian Mixed Epithelial Carcinoma, Ovarian Mucinous Cystadenocarcinoma, Ovarian Serous Cystadenocarcinoma, Ovarian Undifferentiated Adenocarcinoma, Stage IIA Fallopian Tube Cancer, Stage IIA Ovarian Epithelial Cancer, Stage IIA Primary Peritoneal Cavity Cancer, Stage IIB Fallopian Tube Cancer, Stage IIB Ovarian Epithelial Cancer, Stage IIB Primary Peritoneal Cavity Cancer, Stage IIC Fallopian Tube Cancer, Stage IIC Ovarian Epithelial Cancer, Stage IIC Primary Peritoneal Cavity Cancer, Stage IIIA Fallopian Tube Cancer, Stage IIIA Ovarian Epithelial Cancer, Stage IIIA Primary Peritoneal Cavity Cancer, Stage IIIB Fallopian Tube Cancer, Stage IIIB Ovarian Epithelial Cancer, Stage IIIB Primary Peritoneal Cavity Cancer, Stage IIIC Fallopian Tube Cancer, Stage IIIC Ovarian Epithelial Cancer, Stage IIIC Primary Peritoneal Cavity Cancer, Stage IV Fallopian Tube Cancer, Stage IV Ovarian Epithelial Cancer, Stage IV Primary Peritoneal Cavity Cancer
    Ixabepilone in Treating Patients With Recurrent or Persistent Uterine Cancer
    Duke University Medical Center
    Durham, North Carolina 27710
    Recurrent Uterine Sarcoma, Uterine Carcinosarcoma
    A Study of Chemotherapy and Ramucirumab vs. Chemotherapy Alone in Second Line Non-small Cell Lung Cancer Participants Who Received Prior First Line Platinum Based Chemotherapy
    For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.
    Durham, North Carolina
    Non Small Cell Lung Cancer