Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IVA Colon Cancer, Stage IVA Rectal Cancer, Stage IVB Colon Cancer, Stage IVB Rectal Cancer

Dermatologic Complications, Malignant Neoplasm, Pain

Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndrome, Myelofibrosis

B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia, Cognitive/Functional Effects, Neurotoxicity, Pain, Philadelphia Chromosome Positive Childhood Precursor Acute Lymphoblastic Leukemia, Therapy-related Toxicity, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Childhood Acute Lymphoblastic Leukemia

Lymphoma, Neurotoxicity, Therapy-related Toxicity

Multiple Myeloma

Adult Diffuse Astrocytoma, Adult Mixed Glioma, Adult Oligodendroglioma, Cognitive/Functional Effects, Neurotoxicity, Psychosocial Effects of Cancer and Its Treatment, Seizure

Hematopoietic Neoplasm

Hematopoietic Neoplasm

Prostate Cancer, Psychosocial Effects of Cancer and Its Treatment, Radiation Toxicity, Sexual Dysfunction

Multiple Myeloma, Multiple Myeloma in Relapse, Refractory Multiple Myeloma, Mantle Cell Lymphoma in Relapse, Diffuse Large B Cell Lymphoma in Relapse

Hematopoietic Neoplasm

Breast Cancer

Breast Cancer, Cancer Survivor, Hot Flashes

Soft Tissue Sarcoma

Barrett Esophagus, Esophageal Cancer

Acute Myelogenous Leukemia (AML)

Multiple Myeloma

Multiple Myeloma

Smoking Cessation

CD27 Expressing B-cell Malignancies, CD27 Expressing Solid Tumors, Chronic Lymphocytic Leukemia, Burkett's Lymphoma, Mantle Cell Lymphoma, Primary Lymphoma of the Central Nervous System, Marginal Zone B Cell Lymphoma, Solid Tumor, Metastatic Melanoma, Renal (Clear) Cell Carcinoma, Hormone-refractory Prostate Adenocarcinoma, Ovarian Cancer, Colorectal Adenocarcinoma, Non-small Cell Lung Cancer, Melanoma (Solid Tumor Expansion Arm Only)

Childhood Cerebral Astrocytoma/Malignant Glioma, Childhood High-grade Cerebellar Astrocytoma, Childhood High-grade Cerebral Astrocytoma, Childhood Infratentorial Ependymoma, Childhood Mixed Glioma, Childhood Oligodendroglioma, Childhood Supratentorial Ependymoma, Recurrent Childhood Cerebellar Astrocytoma, Recurrent Childhood Cerebral Astrocytoma, Recurrent Childhood Ependymoma, Recurrent Childhood Subependymal Giant Cell Astrocytoma

Non Small Cell Lung Cancer (NSCLC)

Acute Lymphoblastic Leukemia

Ulcerative Colitis

Breast Cancer, Brain Metastases

Relapsed Peripheral T-Cell Lymphoma, Refractory Peripheral T-Cell Lymphoma

Colorectal Cancer Metastatic

CHOLELITHIASIS

Locally Recurrent Breast Cancer, Metastatic Breast Cancer

ST Segment Elevation Myocardial Infarction

Kidney Cancer, Liver Cancer

Low-grade Glioma

Neuromyelitis Optica, Neuromyelitis Optica Spectrum Disorder, Recurrent Idiopathic Longitudinally Extensive Transverse Myelitis

Childhood Hepatocellular Carcinoma, Papillary Thyroid Cancer, Previously Treated Childhood Rhabdomyosarcoma, Recurrent Childhood Liver Cancer, Recurrent Childhood Rhabdomyosarcoma, Recurrent Thyroid Cancer, Recurrent Wilms Tumor and Other Childhood Kidney Tumors

Recurrent Malignant Mesothelioma, Stage IA Malignant Mesothelioma, Stage IB Malignant Mesothelioma, Stage II Malignant Mesothelioma, Stage III Malignant Mesothelioma, Stage IV Malignant Mesothelioma

Leukemia

Metastatic Colorectal Cancer, Colorectal Cancer

Ovarian Cancer

Colorectal Cancer

Chronic Myelomonocytic Leukemia, de Novo Myelodysplastic Syndromes, Previously Treated Myelodysplastic Syndromes, Refractory Anemia With Excess Blasts, Secondary Myelodysplastic Syndromes

Advanced NET of GI Origin, Advanced NET of Lung Origin, Neuroendocrine Tumors

Renal Impairment, Kidney Diseases, Urologic Diseases, Cancer, Hypothermia, Kidney Cancer

Stage IV Non-small Cell Lung Cancer

Breast Cancer

Unspecified Adult Solid Tumor, Protocol Specific

Neurofibromatosis Type 1, Recurrent Childhood Pilocytic Astrocytoma, Recurrent Childhood Visual Pathway Glioma

Breast Cancer

Metastatic Castration Resistant Prostate Cancer

Advanced Cancers, DLBCL, Lymphoma

Relapsed Multiple Myeloma, Refractory Multiple Myeloma

Leukemia, Myeloid, Acute

Myelodysplastic Syndrome

Dose Escalation, Safety, Preliminary Efficacy, Advanced Solid Tumors, Metastatic Breast Cancer, Advanced Pancreatic Adenocarcinoma, Metastatic Colorectal Cancer, Recurrent Glioblastoma Multiforme

Carcinoid Tumor of the Small Bowel, Neuroendocrine Tumour

Hodgkin Lymphoma, Adult

Advanced Renal Cell Carcinoma, Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma

Myelodysplastic Syndrome, MDS, Trisomy 8

Stricture, Obstruction, Cancer

Mesothelioma

Breast Cancer, Pain, Postoperative, BRCA1 Mutation, BRCA2 Mutation, Breast Diseases, Neoplasms

Non-Hodgkin's Lymphoma, Hodgkin Lymphoma, Multiple Myeloma, Chronic Myelogenous Leukemia

Solid Tumors

Myelodysplastic Syndrome

B-cell Childhood Acute Lymphoblastic Leukemia, Childhood Diffuse Large Cell Lymphoma, L3 Childhood Acute Lymphoblastic Leukemia, Stage III Childhood Large Cell Lymphoma, Stage IV Childhood Large Cell Lymphoma, Untreated Childhood Acute Lymphoblastic Leukemia

Obesity, Overweight

Childhood Central Nervous System Choriocarcinoma, Childhood Central Nervous System Embryonal Tumor, Childhood Central Nervous System Germ Cell Tumor, Childhood Central Nervous System Germinoma, Childhood Central Nervous System Mixed Germ Cell Tumor, Childhood Central Nervous System Teratoma, Childhood Central Nervous System Yolk Sac Tumor, Childhood Pineal Parenchymal Tumor

Recurrent Breast Cancer, Recurrent Fallopian Tube Cancer, Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor, Recurrent Primary Peritoneal Cavity Cancer, Stage IIA Ovarian Epithelial Cancer, Stage IIA Ovarian Germ Cell Tumor, Stage IIA Primary Peritoneal Cavity Cancer, Stage IIB Ovarian Epithelial Cancer, Stage IIB Ovarian Germ Cell Tumor, Stage IIB Primary Peritoneal Cavity Cancer, Stage IIC Ovarian Epithelial Cancer, Stage IIC Ovarian Germ Cell Tumor, Stage IIC Primary Peritoneal Cavity Cancer, Stage IIIA Breast Cancer, Stage IIIA Ovarian Epithelial Cancer, Stage IIIA Ovarian Germ Cell Tumor, Stage IIIA Primary Peritoneal Cavity Cancer, Stage IIIB Breast Cancer, Stage IIIB Ovarian Epithelial Cancer, Stage IIIB Ovarian Germ Cell Tumor, Stage IIIB Primary Peritoneal Cavity Cancer, Stage IIIC Breast Cancer, Stage IIIC Ovarian Epithelial Cancer, Stage IIIC Ovarian Germ Cell Tumor, Stage IIIC Primary Peritoneal Cavity Cancer

Amyotrophic Lateral Sclerosis

Peripheral Neuropathy

Pancreatic Cancer Pain

Brain Neoplasm, Breast Neoplasm, Endocrine Gland Neoplasm, Gastrointestinal Neoplasm, Genitourinary Neoplasm, Gynecological Neoplasm, Head and Neck Neoplasm, Lung Neoplasm, Melanoma, Sarcoma