Advanced Solid Tumors

Relapsed or Refractory Solid Tumors

Breast Cancer

Lung Cancer

Stage IV Pancreatic Cancer

Melanoma

ST Segment Elevation Myocardial Infarction

Kidney Cancer, Liver Cancer

Melanoma

Neuromyelitis Optica, Neuromyelitis Optica Spectrum Disorder, Recurrent Idiopathic Longitudinally Extensive Transverse Myelitis

Metastatic Pancreatic Adenocarcinoma, Pancreatic Cancer, Metastatic Pancreatic Cancer

Colorectal Cancer

Chronic Myelomonocytic Leukemia, de Novo Myelodysplastic Syndromes, Previously Treated Myelodysplastic Syndromes, Refractory Anemia With Excess Blasts, Secondary Myelodysplastic Syndromes

Combined Type Small Cell Lung Cancer, Fusiform Type Small Cell Lung Cancer, Lymphocyte-like Type Small Cell Lung Cancer, Polygonal Type Small Cell Lung Cancer, Recurrent Small Cell Lung Cancer

Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, Stage IV Pancreatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific

Breast Cancer

Breast Cancer

Prostate Cancer

Advanced Cancers, DLBCL, Lymphoma

Myelodysplastic Syndrome, MDS, Trisomy 8

Solid Tumors

Metastatic Castration-Resistant Prostate Cancer

Solid Tumors

Adult Primary Hepatocellular Carcinoma, Recurrent Adult Primary Liver Cancer

Neoplasms by Site

Unspecified Adult Solid Tumor, Protocol Specific

Hepatocellular Carinoma

Refractory Multiple Myeloma

Adult Alveolar Soft-part Sarcoma, Adult Angiosarcoma, Adult Epithelioid Sarcoma, Adult Extraskeletal Chondrosarcoma, Adult Fibrosarcoma, Adult Leiomyosarcoma, Adult Liposarcoma, Adult Neurofibrosarcoma, Chondrosarcoma, Endometrial Stromal Sarcoma, Mast Cell Sarcoma, Metastatic Adult Malignant Fibrous Histiocytoma of Bone, Ovarian Carcinosarcoma, Ovarian Sarcoma, Recurrent Adult Malignant Fibrous Histiocytoma of Bone, Recurrent Adult Soft Tissue Sarcoma, Small Intestine Leiomyosarcoma, Stage III Adult Soft Tissue Sarcoma, Stage IV Adult Soft Tissue Sarcoma

Relapsed or Refractory Systemic Light Chain Amyloidosis

Follicular Lymphoma

B-cell Adult Acute Lymphoblastic Leukemia, Blastic Phase Chronic Myelogenous Leukemia, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia, Untreated Adult Acute Lymphoblastic Leukemia

Advanced Cancer

Oropharyngeal Neoplasms

Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma, Recurrent Metastatic Squamous Neck Cancer With Occult Primary, Recurrent Salivary Gland Cancer, Recurrent Squamous Cell Carcinoma of the Hypopharynx, Recurrent Squamous Cell Carcinoma of the Larynx, Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity, Recurrent Squamous Cell Carcinoma of the Nasopharynx, Recurrent Squamous Cell Carcinoma of the Oropharynx, Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity, Recurrent Verrucous Carcinoma of the Larynx, Recurrent Verrucous Carcinoma of the Oral Cavity, Salivary Gland Squamous Cell Carcinoma, Stage III Salivary Gland Cancer, Stage III Squamous Cell Carcinoma of the Hypopharynx, Stage III Squamous Cell Carcinoma of the Larynx, Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity, Stage III Squamous Cell Carcinoma of the Nasopharynx, Stage III Squamous Cell Carcinoma of the Oropharynx, Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity, Stage III Verrucous Carcinoma of the Larynx, Stage III Verrucous Carcinoma of the Oral Cavity, Stage IV Squamous Cell Carcinoma of the Hypopharynx, Stage IV Squamous Cell Carcinoma of the Nasopharynx, Stage IVA Salivary Gland Cancer, Stage IVA Squamous Cell Carcinoma of the Larynx, Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity, Stage IVA Squamous Cell Carcinoma of the Oropharynx, Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity, Stage IVA Verrucous Carcinoma of the Larynx, Stage IVA Verrucous Carcinoma of the Oral Cavity, Stage IVB Salivary Gland Cancer, Stage IVB Squamous Cell Carcinoma of the Larynx, Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity, Stage IVB Squamous Cell Carcinoma of the Oropharynx, Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity, Stage IVB Verrucous Carcinoma of the Larynx, Stage IVB Verrucous Carcinoma of the Oral Cavity, Stage IVC Salivary Gland Cancer, Stage IVC Squamous Cell Carcinoma of the Larynx, Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity, Stage IVC Squamous Cell Carcinoma of the Oropharynx, Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity, Stage IVC Verrucous Carcinoma of the Larynx, Stage IVC Verrucous Carcinoma of the Oral Cavity, Tongue Cancer, Untreated Metastatic Squamous Neck Cancer With Occult Primary

Stage I Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple Myeloma

Refractory Multiple Myeloma

Non-small Cell Lung Cancer(NSCLC)

Tuberous Sclerosis Complex-associated Refractory Seizures

Prostate Cancer

Shoulder Weakness Following Neck Dissection Surgery

Anemia, Primary Myelofibrosis, Secondary Myelofibrosis

Adenosquamous Cell Lung Cancer, Recurrent Non-small Cell Lung Cancer, Squamous Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer

CML

Advanced Pancreatic Cancer, Metastatic Pancreatic Cancer, Pancreatic Adenocarcinoma

Malignant Solid Tumors

Chronic Myelogenous Leukemia

Prostate Cancer

Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, Post Essential Thrombocythemia Myelofibrosis

Primary Liver Cancer, Solid Tumors, Lymphoma

Cancer

Oncology, BRCA Mutated, High Grade Serous Ovarian Cancer, BRCA Mutated Breast Cancer

Dyspnea, Non-small Cell Lung Cancer, Small Cell Lung Cancer

Bladder Cancer

Solid Tumors

Locally Advanced Rectal Cancer

Brain and Central Nervous System Tumors, Pediatric Germ Cell Tumor, Extragonadal Germ Cell Tumor

Colorectal Cancer

Multiple Myeloma

Colorectal Cancer

Colorectal Cancer

Colorectal Cancer

Metastatic Cancer

Esophageal Cancer

Lymphoma

Brain and Central Nervous System Tumors

Brain and Central Nervous System Tumors

Lymphoma

Breast Cancer

Breast Cancer

Brain and Central Nervous System Tumors

Esophageal Cancer, Gastric Cancer

Gastric Cancer, Pancreatic Cancer

Breast Cancer, Metastatic Cancer, Pain, Prostate Cancer

Fatigue, Unspecified Adult Solid Tumor, Protocol Specific