Inclusion Criteria:

- 35 years of age or older

- While male patients will not be explicitly excluded, it is expected that all patients
in this study will be women

- Diagnostic findings from prior mammography suspicious for, or highly suggestive of,
breast malignancy -BIRADS (Breast Imaging Reporting and Data System) categories 4 and
5

- Scheduled for ultrasound or stereotactic core biopsy

- Ability to lie still on a table top for up to 10 minutes, longer than the typical
breast CT duration.

- Ability to understand risks, procedures, and benefits involved

Exclusion Criteria:

- Recent breast biopsy

- History of breast augmentation implant

- Pregnant or Positive urine pregnancy test (UPT) or currently breast-feeding

- History of moderate or severe adverse reaction to iodinated contrast injection

- Recent serum creatinine ≥ 1.5 mg/dL

- History of Diabetes Mellitus

- Currently taking Glucophage or Glucovance (Metformin)

- History of chronic asthma

- History of allergy to iodine

- Multiple food and/or drug allergy

- Renal disease

- History of pulmonary disease, phobia of breath holding, or other condition that could
prevent the subject from being able to perform the 16 second breath hold