Inclusion Criteria

Inclusion/Exclusion Criteria:

- 18 years of age

- Brain tumor(s) to be resected for clinical reasons.

- Histological pathology confirmation that tumor is of glial origin, WHO Grade II, III
or IV.

- Adequate tissue available for processing as determined by Pathology.

- Adequate decision making ability to review, discuss and sign a consent form to allow
their tumor samples to be used for future human brain tumor biology laboratory
research. Determination of capacity to consent is made by one of the co-investigators
based on clinical assessment.

- Patients opting for the standard treatment regimen for their disease as well as
ongoing clinical trials will be are eligible to participate in this study. Standard
care for newly-diagnosed glioblastomas typically consists of surgical resection
followed by radiotherapy with concomitant temozolomide, followed by adjuvant
temozolomide chemotherapy.