CTP (Computed Tomography Perfusion) Imaging of Lung Cancer
18 Years
N/A
Both
Non Small Cell Lung Cancer
Trial Information
CTP (Computed Tomography Perfusion) Imaging of Lung Cancer
This is an experimental study of CT perfusion (CTP) imaging in subjects with non-small cell
lung cancer. The objectives of this study are to demonstrate the feasibility of CT blood
flow measurements in lung cancer, to develop a foundation for the use of CT blood flow
measurements in lung cancer to assess the response to treatment, and to develop an optimized
CTP imaging protocol for evaluating blood flow in solid body tumors. In this study, tumor
blood flow will be evaluated at baseline and follow-up routine CT examinations of patients
with non-small cell lung cancer, and the response of tumor blood flow will be recorded as a
secondary endpoint. This research study will entail two study visits - one required and one
optional - which will coincide with regularly scheduled standard of care CT scans.
Inclusion Criteria:
adult patients with non small cell lung cancer who receive, or are considered for,
systemic therapy
Exclusion Criteria:
renal failure pregnancy known contrast allergy
-
Type of Study:
Observational
Study Design:
Observational Model: Case-Only, Time Perspective: Prospective
Outcome Measure:
Yield of conducting CTP studies
Outcome Description:
Yield is determined as the percentage of assessable CTP studies, relative to all performed studies
Outcome Time Frame:
2 years
Safety Issue:
No
Principal Investigator
Friedrich Knollmann, MD, PhD
Investigator Role:
Principal Investigator
Investigator Affiliation:
Univeristy of California, Davis
Authority:
United States: Institutional Review Board
Study ID:
393991
NCT ID:
NCT01823094
Start Date:
March 2013
Completion Date:
December 2015
Related Keywords:
- Non Small Cell Lung Cancer
- lung cancer
- computed tomography
- blood flow
- Carcinoma, Non-Small-Cell Lung
- Lung Neoplasms
Name | Location |
|---|---|
| University of California, Davis Medical Center | Sacramento, California |
