Identify Clinical Conditions That Increase Circulating DNA Levels
18 Years
80 Years
Both
Pregnancy, Pulmonary Embolism, Myocardial Infarction, Autoimmune Disease
Trial Information
Identify Clinical Conditions That Increase Circulating DNA Levels
The investigator will collect 8 mL (one and one half teaspoons) of blood one time only. The
investigator may also collect the patient's past medical history, test results and disease
treatment.
Inclusion Criteria:
1. Patients must be adults in one of the following categories:
- Pregnant
- Suffered a pulmonary embolism within the past 48 hours
- Myocardial infarction in the past 48 hours
- Diagnosed with an autoimmune disease
- Adults age 18-80
- Self-declared healthy adults
2. Patients must be willing to undergo a blood draw
3. Patients must provide study-specific informed consent prior to study entry
Exclusion Criteria:
1. Patients not meeting the above inclusion criteria
Type of Study:
Observational
Study Design:
Observational Model: Case Control, Time Perspective: Prospective
Outcome Measure:
Different diseases will be analysed for the levels of DNA circulating in the blood
Outcome Description:
To determine what medical conditions and disease states might increase circulating DNA levels at a magnitude similar to whole body irradiation.
Outcome Time Frame:
blood will be tested up to 1 year after collection
Safety Issue:
No
Principal Investigator
Paul Okunieff, MD
Investigator Role:
Principal Investigator
Investigator Affiliation:
University of Florida
Authority:
United States: Institutional Review Board
Study ID:
407-2012
NCT ID:
NCT01815996
Start Date:
October 2012
Completion Date:
September 2016
Related Keywords:
- Pregnancy
- Pulmonary Embolism
- Myocardial Infarction
- Autoimmune Disease
- Pregnancy
- pulmonary embolism
- myocardial infarction
- autoimmune disease
- healthy controls
- Autoimmune Diseases
- Embolism
- Infarction
- Myocardial Infarction
- Pulmonary Embolism
Name | Location |
|---|---|
| Shands Davis Cancer Center | Gainesville, Florida 32610 |
