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Relation of Consummatory and Anticipatory Food Reward to Obesity


N/A
14 Years
16 Years
Open (Enrolling)
Both
Weight Gain, Food Habits

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Trial Information

Relation of Consummatory and Anticipatory Food Reward to Obesity


Inclusion Criteria:



- We will require that adolescents have age- and sex- adjusted standardized body mass
index (BMI) scores between the 25th and 75th percentile at baseline for inclusion.

- Low risk youth: Lean parents will have a BMI between 18 and 25.

- High risk youth: Obese parents will have a BMI value of greater than 30.

Exclusion Criteria:

- Students who report contraindicators of fMRI (e.g., metal implants, braces, or
pregnancy).

- Current major psychiatric disorders (including substance use disorders, conduct
disorder, oppositional defiant disorder, ADHD, major depression, bipolar disorder,
panic disorder, agoraphobia, or generalized anxiety disorder)

- Current use of analgesics and other psychoactive drugs (e.g., cocaine)

- Serious medical complications (e.g., diabetes)

- Relevant food allergies

- Current smoking

- Current weight loss dieting

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Outcome Measure:

Test whether high-risk youth show abnormalities in consummatory and anticipatory food reward relative to low-risk youth

Outcome Description:

Using fMRI to test whether high-risk youth for obesity show differential neural responses in the striatum, and oral somatosensory and gustatory related brain regions when anticipating and during intake of a palatable food, relative to youth at low risk for obesity.

Outcome Time Frame:

up to 3 years

Safety Issue:

No

Principal Investigator

Eric Stice, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Oregon Research Institute

Authority:

United States: Federal Government

Study ID:

DK080760-01

NCT ID:

NCT01807572

Start Date:

June 2009

Completion Date:

July 2014

Related Keywords:

  • Weight Gain
  • Food Habits
  • Food Habits
  • Obesity
  • Weight Gain

Name

Location
Oregon Research Institute Eugene, Oregon  97403