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Role of Proteomics and Metallomics in Cerebral Vasospasm Following Subarachnoid Hemorrhage


N/A
18 Years
89 Years
Open (Enrolling)
Both
Subarachnoid Hemorrhage, Cerebral Vasospasm, Hydrocephalus

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Trial Information

Role of Proteomics and Metallomics in Cerebral Vasospasm Following Subarachnoid Hemorrhage


Inclusion Criteria:



- Non traumatic SAH documented by CT scan

- Patient with SAH who would need external ventricular drain (EVD) for the management
of hydrocephalus

- Patients with normal pressure Hydrocephalus that require an external drain

- Control (non - hemorrhagic) group - CSF collected from patients with posterior fossa
tumor or stroke with EVD in place for the management of hydrocephalus.

Exclusion Criteria:

- Recent infection within last 1 month of presentation- can increase inflammatory
markers

- Recent surgery or acute myocardial infarction within last 1 month of presentation

- Age > 89 years or < 18 years

Type of Study:

Observational

Study Design:

Observational Model: Case Control, Time Perspective: Prospective

Outcome Measure:

Protein identification and concentration

Outcome Time Frame:

For the duration of CSF drainage, or until the 21st day after admission.

Safety Issue:

No

Principal Investigator

Eric M Deshaies, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

SUNY Upstate Medical University - Neurosurgery

Authority:

United States: Institutional Review Board

Study ID:

IRB#225490

NCT ID:

NCT01799018

Start Date:

April 2011

Completion Date:

April 2013

Related Keywords:

  • Subarachnoid Hemorrhage
  • Cerebral Vasospasm
  • Hydrocephalus
  • Xanthine Oxidase
  • Cerebrospinal fluid
  • Hemorrhage
  • Hydrocephalus
  • Subarachnoid Hemorrhage
  • Vasospasm, Intracranial

Name

Location
State University of New York Upstate Medical University Syracuse, New York  13210