A Phase 1b, Open-label, Multicenter Study of Urelumab (BMS-663513) in Combination With Rituximab in Subjects With Relapsed/Refractory B-cell Malignancies
Intervention model: Dose Escalation (part 1) of study= Sequential Design; Dose Expansion
(part 2) of study= Parallel Design
For additional information, please contact the BMS oncology clinical trial information
service at 855-216-0126 or email MyCancerStudyConnect@emergingmed.com. Please visit
www.BMSStudyConnect.com for more information on clinical trial participation.
Interventional
Allocation: Non-Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Safety and tolerability of Urelumab in combination with Rituximab as measured by incidence of adverse events (AEs), serious AEs, death, vital sign changes, electrocardiograms (ECGs), physical examination results, and laboratory test abnormalities
Up to 60 days after last dose of Urelumab
Yes
Bristol-Myers Squibb
Study Director
Bristol-Myers Squibb
United States: Food and Drug Administration
CA186-017
NCT01775631
March 2013
May 2016
Name | Location |
---|---|
University of Miami Sylvester Comprehensive Cancer Center | Miami, Florida 33136 |
Local Institution | Bronx, New York |
Local Institution | Corona, California |
Local Institution | Fort Lauderdale, Florida |
Local Institution | Arlington, Virginia |
Local Institution | Iowa City, Iowa |
Local Institution | Detroit, Michigan |
Portland Providence Medical Center | Portland, Oregon 97213 |