Development of a Quantitative Tissue Optical Index of Breast Density
The researcher wants to study pre-menopausal patients with hormonal positive breast cancer,
taking tamoxifen to reduce the risk of recurrence. Diffuse optical spectroscopic imaging can
captures breast density functional changes measured by MRI and mammography. The DOSI can
prove the underlying physiological origin of breast density variations and provide detail
functional index suitable for bedside assessment of tamoxifen therapy response.The role of
breast density can predict and establish, this information can help individual women decide
whether to start or continue tamoxifen therapy based on their own risk vs. benefit
assessment.
Observational
Observational Model: Case-Only, Time Perspective: Retrospective
Breast Density
Breast Density
up to 12 months
No
Thomas O' Sullivan, PhD
Principal Investigator
Beckman Laser Institute, UCI
United States: Institutional Review Board
DOD BC120040
NCT01773551
April 2012
April 2016
Name | Location |
---|---|
Beckman Laser Institute Medical clinic | Irvine, California 92612 |