Comparison of Breast Cancer Detection Rate for Prevalent Screen Low-dose Molecular Breast Imaging and Incident Biennial Screen Low-dose Molecular Breast Imaging in Women With Mammographically Dense Breasts

Inclusion Criteria:

1)Past prior screening mammogram within the previous 11-24 months interpreted as
heterogeneously dense or extremely dense and negative or benign [Breast Imaging Reporting
and Data System (BI-RADS) Category 1 or 2]

Exclusion Criteria:

Subjects will be excluded if they:

1. Are unable to understand and sign the consent form

2. Are pregnant or lactating

3. Are physically unable to sit upright and still for 40 minutes

4. Have self-reported signs or symptoms that may suggest breast cancer (palpable mass,
bloody nipple discharge, axillary mass, etc.)

5. Have had needle biopsy within 3 months, or breast surgery or radiation within 1 year
prior to the study

6. Are currently receiving chemotherapy or tamoxifen, raloxifene, or an aromatase
inhibitor for adjuvant therapy or chemoprevention

7. Have undergone bilateral mastectomy

8. Have had a prior MBI within 20 months of scheduled study MBI.