Discovery and Validation of Proteogenomic Biomarker Panels in a Prospective Serial Blood & Urine Monitoring Study of Liver Transplant Recipients
N/A
18 Years
N/A
18 Years
N/A
Not Enrolling
Both
Proteogenomic Monitoring in Liver Transplant Recipients
Both
Proteogenomic Monitoring in Liver Transplant Recipients
Trial Information
Discovery and Validation of Proteogenomic Biomarker Panels in a Prospective Serial Blood & Urine Monitoring Study of Liver Transplant Recipients
Inclusion Criteria:
- Subjects undergoing primary deceased-donor or living donor liver transplantation.
- Subject must be able to understand and provide informed consent.
Exclusion Criteria:
- Need for combined organ transplantation
- Previous solid organ and/or islet cell transplantation
- Infection with HIV
- Allergy to Iodine
- Inability or unwillingness of a participant to comply with study protocol
- Any condition that, in the opinion of the investigator, would interfere with the
participant's ability to comply with study requirements
Type of Study:
Observational
Study Design:
Observational Model: Cohort, Time Perspective: Prospective
Outcome Measure:
Acute Rejection
Outcome Description:
The primary endpoint is the incidence of biopsy proven AR at 3, 12 and 24 months after LT.
Outcome Time Frame:
3 months after liver transplant
Safety Issue:
Yes
Principal Investigator
Josh Levitsky, MD, MS
Investigator Role:
Study Chair
Investigator Affiliation:
Northwestern Univ.
Authority:
United States: Federal Government
Study ID:
DAIT CTOT-14
NCT ID:
NCT01672164
Start Date:
August 2012
Completion Date:
August 2015
Related Keywords:
- Proteogenomic Monitoring in Liver Transplant Recipients
- liver transplantation
Name | Location |
|---|---|
| Cleveland Clinic Foundation | Cleveland, Ohio 44195 |
| Medical University of South Carolina | Charleston, South Carolina 29425-0721 |
| Baylor University Medical Center | Dallas, Texas 75246 |
| Mayo Clinic | Scottsdale, Arizona |
| Northwestern University, Feinberg School of Medicine | Chicago, Illinois 60611 |
| Scripps Center for Organ and Cell Transplantation | La Jolla, California 92037 |
