Osteonecrosis of the Jaw (ONJ) Case Registry

Inclusion Criteria:

- Adult (≥18 years of age) with diagnosis of cancer

- Newly diagnosed, positively-adjudicated ONJ

- ECOG <=2 and expected survival ≥3 months

- Willing to provide access to previous and future medical and dental information

- Subject or subject's legally acceptable representative has provided written informed
consent

Exclusion Criteria:

- History of radiation to the maxillofacial area administered for therapeutic intent in
the treatment of cancer

- Subject will not be available for protocol required study visits, to the best of the
subject and investigator's knowledge.

- Subject has any kind of disorder that, in the opinion of the investigator, may
compromise the ability of the subject to give written informed consent and/or to
comply with all required study procedures.