An International Phase 3 Randomized Trial of Autologous Dendritic Cell Immunotherapy (AGS-003) Plus Standard Treatment of Advanced Renal Cell Carcinoma (ADAPT)
Interventional
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Overall Survival
Duration from randomization to death
From date of subject randomization to date of death; assessed up to 42 months or until 290 deaths have been accrued on study
No
Robert Figlin, MD, FACP
Principal Investigator
Cedars-Sinai Medical Center
United States: Food and Drug Administration
AGS-003-007
NCT01582672
November 2012
December 2015
Name | Location |
---|---|
Washington University School of Medicine | Saint Louis, Missouri 63110 |
Fox Chase Cancer Center | Philadelphia, Pennsylvania 19111 |
Loyola University Medical Center | Maywood, Illinois 60153 |
East Jefferson General Hospital | Metairie, Louisiana 70011 |
Lehigh Valley Hospital | Allentown, Pennsylvania 18103 |
Virginia Mason Medical Center | Seattle, Washington 98111 |
Rush University Medical Center | Chicago, Illinois 60612-3824 |
Madigan Army Medical Center | Tacoma, Washington 98431-5048 |
Hartford Hospital | Hartford, Connecticut 06102-5037 |
Ochsner Clinic Foundation | New Orleans, Louisiana 70121 |
University of Oklahoma Health Sciences Center | Oklahoma City, Oklahoma 73104 |
Indiana University Melvin and Bren Simon Cancer Center | Indianapolis, Indiana 46202-5289 |
Massachusetts General Hospital | Boston, Massachusetts 02114-2617 |
University of Pittsburgh Medical Center | Pittsburgh, Pennsylvania 15213 |
University of Minnesota | Minneapolis, Minnesota 55455 |
Tulane University Medical Center | New Orleans, Louisiana 70112 |
University of Utah | Salt Lake City, Utah |
Duke University Medical Center | Durham, North Carolina 27710 |
SUNY Upstate Medical University | Syracuse, New York 13210 |
Oregon Health Sciences University | Portland, Oregon |
Nebraska Methodist Hospital | Omaha, Nebraska 68114 |
Saint Alphonsus Regional Medical Center | Boise, Idaho 83706 |
California Pacific Medical Center Research Institute | San Francisco, California 94115 |
H. Lee Moffitt Cancer Center & Research Institute | Tampa, Florida 33612 |
University of Colorado Hospital | Denver, Colorado 80262 |
Providence Portland Medical Center | Portland, Oregon 97213-3635 |
M.D. Anderson Cancer Center | Houston, Texas 77030 |
Dartmouth Hitchcock Medical Center | Lebanon, New Hampshire 03756 |
Urological Associates Of Lancaster | Lancaster, Pennsylvania 17604-3200 |
Albany Medical Center | Albany, New York 12208 |
University of Maryland, Greenebaum Cancer Center | Baltimore, Maryland 21201 |
Vanderbilt University School of Medicine | Nashville, Tennessee 37232-6307 |
David Geffen School of Medicine at UCLA | Los Angeles, California 90095 |
Carolina Urologic Research Center | Myrtle Beach, South Carolina 29572 |
University of Kansas Cancer Center | Kansas City, Kansas 66160 |
University of Iowa Hospital and Clinics | Iowa City, Iowa 52242 |
University of Virginia Health System | Charlottesville, Virginia 22903 |
Urology of Indiana | Indianapolis, Indiana 46254 |
Mayo Clinic - Rochester | Rochester, Minnesota 55905 |
Lahey Clinic Medical Center | Burlington, Massachusetts 01805 |
MD Anderson - Orlando | Orlando, Florida 32806 |
Aurora Health Care | Elkhorn, Wisconsin 53121 |
Medical University of South Carolina (MUSC) | Charleston, South Carolina 29425 |
Signal Point Clinical Research Center, LLC | Middletown, Ohio 45042 |
The Urology Center of Colorado | Denver, Colorado 80211 |
Urology of Virginia | Newport News, Virginia 23606 |
Levine Cancer Institute | Charlotte, North Carolina 28211 |
John Theurer Cancer Center at Hackensack UMC | Hackensack, New Jersey 07601 |
Mercy Cancer Center | Toledo, Ohio 43623 |
Jewish Hospital & St. Mary's Healthcare | Louisville, Kentucky 40245 |
Associated Medical Professionals of New York | Syracuse, New York 13210 |
Edward Hines Jr VA Hospital | Hines, Illinois 60141 |
Idaho Urologic Institute | Meridian, Idaho 83642 |
Samuel Oschin Cancer Center at Cedars-Sinai Medical Center | Los Angeles, California |
Vanguard Health Chicago | Chicago, Illinois 60640 |
Associated Urologists of North Carolina | Raleigh, North Carolina 27607 |
University of Texas Medical Branch - Galveston | Galveston, Texas 77555 |
Advanced Urology, P.C. | Parker, Colorado 80134 |
Emory Univeristy Hospital | Atlanta, Georgia 30322 |
University of Illinois Hospital | Chicago, Illinois 60612 |
Edward H. Kaplan and Associates | Skokie, Illinois 60076 |
Southern Illinois University - Simmons Cancer Institute | Springfield, Illinois 62702 |
Franciscan St. Francis Health - Franciscan Physician Network Oncology and Hematology Specialists | Indianapolis, Indiana 46237 |
Greater Baltimore Medical Center (GBMC) | Baltimore, Maryland 21204 |
Karmanos Cancer Institute - Wayne State University School of Medicine | Detroit, Michigan 48201 |
Cancer and Hematology Clinics of Western Michigan - Spectrum Health | Grand Rapids, Michigan 49503 |
Hematology Oncology Associates of CNY | East Syracuse, New York 13057 |
New York Medical College - Urology Center of Westchester | Hawthorne, New York 10532 |
North Shore Long Island Jewish Hospital System - Monter Cancer Center | New Hyde Park, New York 11040 |
Mount Sinai School of Medicine - Medical Center | New York, New York 10029 |
Strong Memorial Hospital - University of Rochester Medical Center | Rochester, New York 14642 |
Wake Forest Baptist Health - Wake Forest University School of Medicine | Winston-Salem, North Carolina 27157 |
TriState Urologic Services PSC Inc. The Urology Group | Cincinnati, Ohio 45212 |
St. Luke's Hospital - Bethlehem Campus | Bethlehem, Pennsylvania 18015 |
The Pennsylvania State University - Penn State | Hershey, Pennsylvania 17033 |
Hershey Cancer Institute - Hershey Medical Center | Hershey, Pennsylvania 17033 |
Greenville Hospital System - Cancer Centers of the Carolinas | Greenville, South Carolina 29605 |
Seattle Cancer Center | Seattle, Washington 98109 |