The BEACON Study (Breast Cancer Outcomes With NKTR-102): A Phase 3 Open-Label, Randomized, Multicenter Study of NKTR-102 Versus Treatment of Physician's Choice (TPC) in Patients With Locally Recurrent or Metastatic Breast Cancer Previously Treated With an Anthracycline, a Taxane and Capecitabine
Interventional
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Overall Survival
To compare overall survival (OS) of patients who received NKTR-102 given once every 21 days (q21d) to patients who received Treatment of Physicians Choice (TPC) selected from the following list of seven single agent intravenous therapies: eribulin, ixabepilone,vinorelbine, gemcitabline, paclitaxel, docetaxel or nab-paclitaxel
36 Months
No
Robert Medve, MD
Study Director
Nektar Therapeutics
United States: Food and Drug Administration
11-PIR-11
NCT01492101
December 2011
Name | Location |
---|---|
Mayo Clinic | Rochester, Minnesota 55905 |
Beth Israel Medical Center | New York, New York 10003 |
Virginia Mason Medical Center | Seattle, Washington 98111 |
Cooper University Hospital | Camden, New Jersey 08103 |
Virginia Oncology Associates | Newport News, Virginia 23606 |
Dartmouth-Hitchcock Medical Center | Lebanon, New Hampshire 03756 |
Cancer Centers of the Carolinas | Greenville, South Carolina 29605 |
Wilshire Oncology Medical Group, Inc. | Rancho Cucamonga, California 91730 |
Coborn Cancer Center | Saint Cloud, Minnesota 56303 |
Missouri Cancer Associates | Columbia, Missouri 65201 |
Stanford University School of Medicine | Stanford, California 94305-5317 |
Seattle Cancer Care Alliance | Seattle, Washington 98109 |
University of Minnesota | Minneapolis, Minnesota 55455 |
Rocky Mountain Cancer Centers | Thornton, Colorado 80260 |
Mayo Clinic in Florida | Jacksonville, Florida 32224 |
University of Virginia | Charlottesville, Virginia 22908 |
Cancer Care Northwest | Spokane, Washington 99202 |
University of California San Francisco | San Francisco, California 941104206 |
SUNY Upstate Medical University | Syracuse, New York 13210 |
New York Oncology Hematology, P.C. | Albany, New York 12208 |
Emory University | Atlanta, Georgia 30322 |
Kaiser Permanente | Sacramento, California |
Minnesota Oncology Hematology, P.A. | Minneapolis, Minnesota 55407 |
Hematology-Oncology Associates of Northern NJ, PA | Morristown, New Jersey 07962 |
Medical Oncology Associates of Wyoming Valley, PC | Kingston, Pennsylvania 18704 |
Hematology Oncology Associates of the Treasure Coast | Port St. Lucie, Florida 34952 |
The West Clinic | Memphis, Tennessee 38120 |
The Cancer Institute of New Jersey | New Brunswick, New Jersey 08901 |
Northwest Georgia Oncology Centers, P.C. | Marietta, Georgia 30060 |
University of Miami School of Medicine | Miami, Florida 33136 |
University of Southern California | Los Angeles, California 90033 |
University of Cincinnati | Cincinnati, Ohio 45267-0502 |
Missouri Baptist Medical Center | Saint Louis, Missouri 63131 |
Cornell University | New York, New York 10021 |
Kansas City Cancer Center | Kansas City, Kansas 66112 |
Oncology Specialists | Park Ridge, Illinois 60068 |
Maryland Oncology Hematology, P.A. | Columbia, Maryland 21044 |
Sarah Cannon Research Institute | Nashville, Tennessee 37203 |
Desert Hematology Oncology Medical Group | Rancho Mirage, California 92270 |
Cancer Care Centers of South Texas | San Antonio, Texas 78229 |
Yakima Valley Memorial Hospital/North Star Lodge | Yakima, Washington 98902 |
Texas Oncology-Austin Midtown | Austin, Texas 78705 |
Northeast Georgia Cancer Care | Athens, Georgia 30607 |
Advanced Medical Specialties | Miami, Florida 33176 |
Northwest Cancer Specialists, P.C. | Portland, Oregon 97227 |
Washington University in St. Louis | St. Louis, Missouri 63110 |
Carolinas Hematology Oncology Associates | Charlotte, North Carolina 28203 |
Florida Cancer Research Institute | Davie, Florida |
Louisville Oncology Clinical Research Program | Louisville, Kentucky 40202 |
Central Georgia Cancer Care | Macon, Georgia 31201 |
Peachtree Hematology Oncology Consultants | Atlanta, Georgia 30309 |
Sarah Cannon Research Institute (SCRI) | Nashville, Tennessee 37203 |
Signal Point Clinical Research Center | Middletown, Ohio 45042 |
UNM Cancer Center | Albuquerque, New Mexico 87106 |
Texas Oncology-Tyler | Tyler, Texas 75702 |
Frontier Cancer Center and Blood Institute | Billings, Montana 59102 |
Texas Oncology-Abilene | Abilene, Texas 79606 |
Arizona Oncology Associates, PC - NAHOA | Sedona, Arizona 86336 |
Texas Oncology-Dallas Presbyterian Hospital | Dallas, Texas 75231 |
Texas Oncology-Memorial City | Houston, Texas 77024 |
Texas Oncology-Mesquite | Mesquite, Texas 75150 |
Texas Oncology-Midland Allison Cancer Center | Midland, Texas 79701 |
Texas Oncology-Baylor Charles A. Sammons Cancer Center | Dallas, Texas 75246 |
Texas Oncology-Beaumont, Mamie McFaddin Ward Cancer Center | Beaumont, Texas 77702 |
PMK Medical Group, Inc., dba Ventura County Hematology Oncology Specialists | Oxnard, California 93030 |
Cancer Team Bellin Health | Green Bay, Wisconsin 54313 |
Texas Oncology-Medical City Dallas | Dallas, Texas 75230-2510 |
Texas Oncology - Sherman | Sherman, Texas 75090-0504 |
Texas Oncology-Lewisville | Lewisville, Texas ??75067 |
Providence Health System - Southern California d/b/a Roy and Patricia Disney Family Cancer Center | Burbank, California 91505 |
Illinois Cancer Care, P.C. | Peoria, Illinois 61547 |
Hall-Perrine Cancer Center, 3rd Floor | Cedar Rapids, Iowa 52403 |
Sciode Medical Associates, PLLC, d.b.a. Eastchester Center for Cancer Care | Bronx, New York 10469 |
DUMC, Duke South | Durham, North Carolina 27710 |
Sanford Research/USD | Fargo, North Dakota 58122 |
Texas Oncology-Bedford | Bedford, Texas 76022 |
Texas Oncology-Denton South | Denton, Texas 76210 |
Texas Oncology-Fort Worth | Fort Worth, Texas 76104 |
Texas Oncology, P.A. - Plano | Plano, Texas 92270 |
Oncology and Hematology Associates of Southwest Virginia, Inc., DBA Blue Ridge Cancer Care | Salem, Virginia 24153 |
Pre clinical Science Bldg LR3 | Washington, District of Columbia 20007 |
Medstar | Washington DC, District of Columbia 20010 |
Summit Cancer Care, P.C. | Savannah, Georgia 31405 |
The University of Chicago Medicine | Chicago, Illinois 60637 |
IU Health Simon Cancer Center | Indianapolis, Indiana 46202 |
Monte fiore | Bronx, New York 10461 |
Comprehensive Breast Cancer | Columbus, Ohio 43212 |
Sanford Research/USD | Sioux Falls, South Dakota 57104 |