Pilot Study of Neuropsychologic and Electrophysiological Features of Cancer-Related Cognitive Side Effects in Racial and Ethnic Minority Breast Cancer Patients
Inclusion Criteria:
- Is at least 18 years old, but not older than 61 years old;
- Is female;
- Is Hispanic of any race or Black/African American
- Is fluent in English (see explanation in Section 7.0 Assessment / Evaluation Plan -
Language Determination);
- Has a diagnosis of breast cancer (Stage I-III);
- Is treatment naïve and scheduled to receive chemotherapy, radiation, or endocrine
therapy.
Healthy Control Subject Inclusion Criteria
- Is at least 18 years old, but not older than 61 years old;
- Is female;
- Is Hispanic or Black Non-Hispanic;
- Is fluent in English
Exclusion Criteria:
- Participants with neurologic illnesses affecting cognition, (i.e., Traumatic Brain
Injury with a loss of consciousness >30 min., etc.) or severe psychiatric illness
(i.e., schizophrenia, bipolar disorder, etc.);
- A hearing or visual deficit that impairs the ability to participate in the EEG tasks.
- Any condition which prevents application of the 160 EEG electrodes spaced evenly
across the participant's scalp, which includes dreadlocks, and hair extensions
applied by weaving, braiding, gluing, or clips-. unless the participants are willing
to undo these styles prior to the EEG.
- Mini-Mental State Exam (MMSE) <16 (telephone version); MMSE <20 (in-person version)
- Prior chemotherapy for any malignancy
- Regularly taking opiates or take a daily, morning benzodiazepine or have taken a prn
benzodiazepine prior to the assessment.
Healthy Control Subject Exclusion Criteria
- Current or historical cancer diagnosis (a previous diagnosis of basal cell skin
carcinoma is allowable)
- History of neurologic illnesses affecting cognition, (i.e., Traumatic Brain Injury
with a loss of consciousness >30 min., etc.) or severe psychiatric illness (i.e.,
schizophrenia, bipolar disorder, etc.);
- A hearing or visual deficit that impairs the ability to participate in the EEG tasks.
- Any condition which prevents application of the 160 EEG electrodes spaced evenly
across the participant's scalp, which includes dreadlocks, and hair extensions
applied by weaving, braiding, gluing, or clips-. unless the participants are willing
to undo these styles prior to the EEG
- Mini-Mental State Exam (MMSE) <16 (telephone version); MMSE <20 (in-person version)
- Regularly taking opiates or takes a daily, morning benzodiazepine or has taken a prn
benzodiazepine prior to the assessment.