Molecular Characterization of Lung Cancer: A Collaboration With the Cancer Genome Atlas Project (TGCA)
OBJECTIVES:
- To identify and characterize single nucleotide variations (SNVs) in non-small cell lung
cancer (NSCLC) specimens.
- To identify and characterize structural variations in the genomes of NSCLC specimens.
- To identify and characterize other genomic alterations including, but not limited to,
expression profiling and methylation.
OUTLINE: DNA and RNA extracted from archived specimens are analyzed for single nucleotide
variations, structural variations in the genomes, and other genomic alterations including,
but not limited to, gene expression profiling and methylation. Clinical data related to
disease, treatment, and recurrence from each patient sample is also collected.
Observational
N/A
Identification and characterization of SNVs in primary adenocarcinoma of the lung or squamous cell carcinoma of the lung
No
Ramaswamy Govindan, MD
Principal Investigator
Washington University Siteman Cancer Center
Unspecified
CDR0000706375
NCT01414595
March 2012
Name | Location |
---|---|
Roswell Park Cancer Institute | Buffalo, New York 14263 |
CCOP - Christiana Care Health Services | Wilmington, Delaware 19899 |
Rhode Island Hospital Comprehensive Cancer Center | Providence, Rhode Island 02903 |
Greenebaum Cancer Center at University of Maryland Medical Center | Baltimore, Maryland 21201 |
Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center | Los Angeles, California 90048-1865 |
Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis | St. Louis, Missouri 63110 |
Cancer Institute of New Jersey at Cooper - Voorhees | Voorhees, New Jersey 08043 |
Tunnell Cancer Center at Beebe Medical Center | Lewes, Delaware 19958 |
Union Hospital of Cecil County | Elkton MD, Maryland 21921 |
Duke Cancer Institute | Durham, North Carolina 27710 |
Miriam Hospital | Providence, Rhode Island 02906 |