Psychosocial Benefits of Exercise in Endometrial Cancer Survivors
Endometrial cancer is the most prevalent gynecologic cancer in women. Because of its
excellent 5 year survival rate of 83%, addressing longer term cancer effects in this group
is an important aspect of cancer survivor care. Unfortunately, women with a history of
endometrial cancer may report persistent levels of fatigue, depression, and anxiety that
are, on average, higher than those of healthy, gynecologic out-patients. Physical activity
is one potential approach to reducing these symptoms, but little is known about the effects
of physical activity in endometrial cancer survivors specifically. Furthermore, current
evidence is insufficient to make recommendations regarding the optimal exercise amount,
type, and duration for improving fatigue, depression, or anxiety after a cancer diagnosis
(any cancer type).
This pilot, randomized trial is unique in its focus on endometrial cancer survivors, a
previously understudied population with a large potential for benefiting from regular
physical activity. Two separate walking intervention groups will work with an exercise
specialist three times a week to walk for either 75 minutes (group 1) or 150 minutes (group
2) weekly. The participants will start out slowly and then gradually increase to the
particular group goal of 75 or 150 minutes. The stretching exercise group will work with an
exercise specialist doing stretching/flexibility exercises three times a week starting with
15 seconds and then gradually increasing to 30 seconds of holding the stretch.
Interventional
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care
fatigue
13-item multi-dimensional fatigue scale [i.e. Fatigue Symptom Inventory (FACT-F)]
Change from baseline at 12 weeks
No
Laura Q. Rogers, MD, MPH
Principal Investigator
Southern Illinois University School of Medicine
United States: Institutional Review Board
ROG-SIU-11-004
NCT01401829
July 2011
September 2013
Name | Location |
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Southern Illinois University School of Medicine | Springfield, Illinois 62794-9658 |