Comparison of Health Related Quality of Life and Other Clinical Parameters Between ThinSeed™ and OncoSeed™ for Permanent Low Dose Rate Implantation in Localized Prostate Cancer

Inclusion Criteria:

- Histologically confirmed adenocarcinoma of the prostate, clinical stage T1c - T2b,
N0, M0

- Greater than or equal to 40 years of age

- Low and Low- Intermediate Risk prostate cancer

- Prostate volumes by TRUS ≤ 60 cc

- I-PSS score < 25 (alpha blockers allowed)

- Signed study-specific informed consent form prior to study entry

Exclusion Criteria:

- Lymph node involvement (N1)

- Evidence of distant metastases (M1)

- Radical surgery for carcinoma of the prostate

- Prior pelvic radiation

- Major medical or psychiatric illness, which in the investigator's opinion would
prevent completion of treatment and would interfere with follow- up or ability to
complete questionnaires

- Hip prosthesis

- Inability or refusal to provide informed consent

- Evidence of Previous TURP

- Prior hormone therapy

- Prior TURP