Phase 1 of Serum IGF II and Cancer: Can IGF II Levels be Used to Monitor and Screen Patients Specifically for Cervical Cancer
Inclusion Criteria:
- Age 18 - 75 years
- Female
- Normal medical history
- Medical history of a single type of cancer confirmed by biopsy or equivalent criteria
- Squamous cell carcinoma of organs other than cervix
- Adenocarcinoma
- Medical history of inflammatory disease
- May be pregnant
- Pap smear positive for Cervical Intraepithelial Neoplasia II or III
- Squamous cell cervical cancer confirmed by biopsy
- Informed consent
- Willingness to submit a blood sample by venipuncture
- Willingness to submit a second blood sample if necessary
Exclusion Criteria:
- Age < 18 or > 75 years
- Medical history of cancer other than cervical cancer, Non-islet-cell tumor
hypoglycemia, Growth hormone deficiency, Acromegaly, Hepatoma, inflammatory disease
in addition to confirmed CIN and cervical cancer