Phase 1 of Serum IGF II and Cancer: Can IGF II Levels be Used to Monitor and Screen Patients Specifically for Cervical Cancer

Inclusion Criteria:

- Age 18 - 75 years

- Female

- Normal medical history

- Medical history of a single type of cancer confirmed by biopsy or equivalent criteria

- Squamous cell carcinoma of organs other than cervix

- Adenocarcinoma

- Medical history of inflammatory disease

- May be pregnant

- Pap smear positive for Cervical Intraepithelial Neoplasia II or III

- Squamous cell cervical cancer confirmed by biopsy

- Informed consent

- Willingness to submit a blood sample by venipuncture

- Willingness to submit a second blood sample if necessary

Exclusion Criteria:

- Age < 18 or > 75 years

- Medical history of cancer other than cervical cancer, Non-islet-cell tumor
hypoglycemia, Growth hormone deficiency, Acromegaly, Hepatoma, inflammatory disease
in addition to confirmed CIN and cervical cancer