Trial Information

Detection of Choroidal Nevus Cells in Vitrectomy Fluid

Approximately 7% of the population has a choroidal nevus, or "freckle," in the back of the
eye. Like a nevus on the skin, there is potential for malignant change to a melanoma.
Dermatologists have the ability to quickly and easily biopsy suspicious skin lesions while
ophthalmologists currently have no way of determining the malignant potential of choroidal
nevi other than a fine needle aspiration (which is invasive and has the potential
complications of bleeding and retinal detachment). This study's sole aim is to see if
choroidal nevi cells are present in the inside fluid of the eye. The investigators plan to
analyze the fluid of the eye, which is routinely removed during retina surgery, to detect
any nevus cells. If the investigators are able to detect these cells, then future studies
may allow us to better classify choroidal nevi for potential malignant change.