Inclusion Criteria:
- BMI at least 25.0 kg/m2
- Diagnosed with Stage I, II, or III breast cancer within past 5 years
- Treatment with total mastectomy or breast-sparing surgical removal of cancer with
clear macroscopic margins, and axillary dissection, followed by adjuvant breast
radiation
- Not scheduled for or currently undergoing chemotherapy
- Accessible geographically and by telephone
- Able to communicate dietary and physical activity data via telephone
- If taking statins, tamoxifen, or aromatase inhibitors; able and willing to remain on
treatment for 6-month study period
- Post-menopausal at diagnosis
Exclusion Criteria:
- Preliminary bloodwork outside of specified ranges
- Evidence of renal insufficiency, liver disease, or congestive heart failure
- Currently taking corticosteroid pills or steroid hormone therapy (including vaginal
estrogen creams)
- Recent initiation (< 3 months ago) of thiazides or β-blockers
- Taking insulin or other antidiabetic drug
- Other primary or recurrent invasive cancer in past 10 years
- Unable to commit to study requirements