Could Dietary Algae Affect Immunity and Viral Counts in People With HIV?
18 Years
N/A
Both
HIV Infections
Trial Information
Could Dietary Algae Affect Immunity and Viral Counts in People With HIV?
Twelve HIV+ patients not on antiretroviral therapy were clinically evaluated and enrolled in
the three-week study. Subjects received 10 algae capsules/d. Laboratory tests of CD4 counts
and HIV RNA were performed at baseline, week 1, week 2, and week 3, and then once a month.
Six subjects continued for between 4 and 14 months. In addition to CD4 lymphocyte counts and
viral loads, subjects were evaluated monthly for Complete Blood Counts (CBC), Liver profile,
Basic Metabolic Panel, and some subjects were evaluated for thyroid function and
cholesterol. All subjects completed standard HIV Quality of Life questionnaires at each
clinic visit.
Inclusion Criteria:
- Clinical diagnosis of HIV
- Able to swallow pills
Exclusion Criteria:
- Allergy to iodine/seafood
- Thyroid disease
- Not taking antiretroviral therapy
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Subject), Primary Purpose: Prevention
Outcome Measure:
Dietary algae influence on CD4 helper cells and HIV viral load
Outcome Description:
The first 6 subjects participated for 3 weeks. After analysis of the results, it was determined that there were no side effects and some indication of benefit. The next 6 subjects participated for up to 14 months.
Outcome Time Frame:
Once a week for first 3 weeks, then once a month
Safety Issue:
Yes
Authority:
United States: Institutional Review Board
Study ID:
Dietary Algae and HIV
NCT ID:
NCT01195077
Start Date:
February 2003
Completion Date:
June 2008
Related Keywords:
- HIV Infections
- HIV
- Dietary intervention
- Algae
- HIV progression
- Algae specific kind
- HIV Infections
- Acquired Immunodeficiency Syndrome
Name | Location |
|---|---|
| Cancer Prevention and Control Program/University of South Carolina | Columbia, South Carolina 29208 |
