A Phase 3, Multi-Site, Open-Label Study Of The Long Term Safety And Tolerability Of 2 Oral Doses Of CP-690,550 In Subjects With Moderate To Severe Chronic Plaque Psoriasis
Phase 3
18 Years
N/A
18 Years
N/A
Open (Enrolling)
Both
Psoriasis
Both
Psoriasis
Trial Information
A Phase 3, Multi-Site, Open-Label Study Of The Long Term Safety And Tolerability Of 2 Oral Doses Of CP-690,550 In Subjects With Moderate To Severe Chronic Plaque Psoriasis
Inclusion Criteria:
- Have participated in qualifying study with CP-690,550 and are 18 years or older with
diagnosis of plaque-type psoriasis (psoriasis vulgaris).
Exclusion Criteria:
- Non-plaque or drug induced forms of psoriasis;
- Cannot discontinue current oral, injectable or topical therapy for psoriasis or
cannot discontinue phototherapy (PUVA or UVB).
- Any uncontrolled significant medical condition.
Type of Study:
Interventional
Study Design:
Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Outcome Measure:
Incidence and severity of adverse events during treatment.
Outcome Time Frame:
Month 1, month 3, and every three months thereafter until approximately April 2017
Safety Issue:
Yes
Principal Investigator
Pfizer CT.gov Call Center
Investigator Role:
Study Director
Investigator Affiliation:
Pfizer
Authority:
United States: Food and Drug Administration
Study ID:
A3921061
NCT ID:
NCT01163253
Start Date:
September 2010
Completion Date:
April 2017
Related Keywords:
- Psoriasis
- chronic
- severe
- treatment
- safety
- CP-690
- 550
- Plaque Psoriasis
- Psoriasis Vulgaris
- Psoriasis
Name | Location |
|---|---|
| Rhode Island Hospital | Providence, Rhode Island 02903 |
| University of California San Diego | La Jolla, California 92093 |
| University of Alabama at Birmingham | Birmingham, Alabama 35294-3300 |
| Oregon Health & Science University | Portland, Oregon 97201 |
| Duke University Medical Center | Durham, North Carolina 27710 |
| University of California San Francisco | San Francisco, California 941104206 |
| Renstar Medical Research | Ocala, Florida 34474 |
| New York University School of Medicine | New York, New York 10016 |
| Tufts Medical Center | Boston, Massachusetts 02111 |
| Wake Forest University Health Sciences | Winston-Salem, North Carolina 27157 |
| Springfield Clinic, LLP | Springfield, Illinois 62703 |
| University of North Carolina at Chapel Hill | Chapel Hill, North Carolina 27599 |
| Cherry Creek Research, Inc. | Denver, Colorado 80246 |
| Minnesota Clinical Study Center | Fridley, Minnesota 55432 |
| Center For Clinical Studies | Houston, Texas 77030 |
| Associates In Research, Inc. | Fresno, California 93720 |
| Healthcare Partners Medical Group | Torrance, California 90503 |
| North Florida Dermatology Associates, PA | Jacksonville, Florida 32204 |
| Schaumburg Dermatology | Schaumburg, Illinois 60194 |
| Dawes Fretzin Clinical Research Group, LLC | Indianapolis, Indiana 46256 |
| Clinical Partners, LLC | Johnston, Rhode Island 02919 |
| Burke Pharmaceutical Research | Hot Springs, Arkansas 71913 |
| Wake Research Associates | Raleigh, North Carolina 27612 |
| New England Research Associates, Llc | Trumbull, Connecticut 06611 |
| Altman Dermatology Associates | Arlington Heights, Illinois 60004 |
| Virginia Clinical Research, Inc. | Norfolk, Virginia 23507 |
| University Hospitals Case Medical Center | Cleveland, Ohio 44106 |
| Suzanne Bruce and Associates, PA | Houston, Texas 77056 |
| Miami Research Associates | Miami, Florida 33173 |
| Park Avenue Dermatology, PA | 1543 Kingsley Ave, Bldg 1 and 16 Orange Park, Florida 32073 |
| Comprehensive Clinical Research | Berlin, New Jersey 08009 |
| Springfield Clinic | Springfield, Illinois 62703 |
| Dermatology Associates of Knoxville, PC | Knoxville, Tennessee 37922 |
| Dermatology Research Associates | Los Angeles, California 90045 |
| Academic Alliance in Dermatology | Tampa, Florida 33615 |
| Hamzavi Dermatology | Fort Gratiot, Michigan 48059 |
| NorthShore University HealthSystem | Evanston, Illinois |
| Oregon Dermatology and Research Center | Portland, Oregon 97210 |
| Horizon Research Group, Inc. | Mobile, Alabama 36608 |
| Dermatology Research Associates | Nashville, Tennessee 37203 |
| International Dermatology Research, Inc. | Miami, Florida |
| Dermatology Consulting Services | High Point, North Carolina |
| Deaconess Clinic Downtown | Evansville, Indiana 47713 |
| Ameriderm Research | Jacksonville, Florida 32216 |
| MedaPhase Inc. | Newnan, Georgia 30263 |
| Radiant Research, Inc. | Greer, South Carolina 29651 |
| The Rockefeller University | New York, New York 10065 |
| Florida Academic Dermatology Center | Miami, Florida 33136 |
| Atlanta Dermatology, Vein & Research Center, P.C. | Alpharetta, Georgia 30022 |
| Dundee Dermatology | West Dundee, Illinois 60118 |
| DermResearch, PLLC | Louisville, Kentucky 40217 |
| Clinical Science Institute | Santa Monica, California 90404 |
| Radiant Research, Inc. | Birmingham, Alabama 35209 |
| Radiant Research, Inc. | Chandler, Arizona 85225 |
| Radiant Research, Inc. | Akron, Ohio 44311 |
| Central Sooner Research | Norman, Oklahoma 73071 |
| Skin Specialists, P.C. | Omaha, Nebraska 68144 |
| Dermatology Specialists, Inc. | Oceanside, California 92056 |
| Skin Search of Rochester, Inc. | Rochester, New York 14623 |
| Arlington Research Center, Inc. | Arlington, Texas 76011 |
| Bakersfield Dermatology and Skin Cancer Medical Group | Bakersfield, California 93309 |
| University of California, Irvine - Dermatology Research | Irvine, California 92697 |
| Expresscare Medical | Los Angeles, California 90045 |
| MedDerm Associates | San Diego, California 92103 |
| Jeremy Ethan Moss, MD, FACP | Bridgeport, Connecticut 06611 |
| The Savin Center, P.C. | New Haven, Connecticut 06511 |
| Peachtree Dermatology Associates Research Center | Atlanta, Georgia 30327 |
| NorthShore University HealthSystem - Division of Dermatology | Skokie, Illinois 60077 |
| Hudson Dermatology | Evansville, Indiana 47714 |
| Dawes Fretzin Dermatology Group | Indianapolis, Indiana 46256 |
| DMIA | Louisville, Kentucky 40207 |
| Quest Diagnostics | Louisville, Kentucky 40217 |
| Massachusetts General Hospital - Clinical Unit for Research Trials and Outcomes in Skin | Boston, Massachusetts 02114 |
| Michigan Center for Research Corporation dba Michigan Center for Skin Care Research | Clinton Township, Michigan 48038 |
| Somerset Skin Centre - Dermcenter | Troy, Michigan 48084 |
| Saint Louis University - Department of Dermatology | Saint Louis, Missouri 63104 |
| Skin Center | Henderson, Nevada 89074 |
| Dartmouth Hitchcock Medical Center - Section of Dermatology | Lebanon, New Hampshire 03756 |
| University of North Carolina at Chapel Hill Hospital | Chapel Hill, North Carolina 27514 |
| Dermatology Associates | Wilmington, North Carolina 28401 |
| New Hanover Medical Research | Wilmington, North Carolina 28401 |
| Triad Dermatology, PA | Winston-Salem, North Carolina 27103 |
| PMG Research of Winston-Salem | Winston-Salem, North Carolina 27103 |
| Piedmont Imaging | Winston-Salem, North Carolina 27103 |
| Jewish Hospital (Chest X-Rays Only) | Cincinnati, Ohio 45236 |
| Paul S. Gillum, MD | Norman, Oklahoma 73069 |
| Baker Allergy, Asthma, and Dermatology Research Center | Lake Oswego, Oregon 97035 |
| University of Pittsburgh Medical Center - Department of Dermatology | Pittsburgh, Pennsylvania 15213 |
| Office of John M. Humeniuk, MD | Greer, South Carolina 29650 |
| Health Concepts | Rapid City, South Dakota 57702 |
| Modern Research Associates, PLLC | Dallas, Texas 75231 |
| InSight Diagnostic Center | Dallas, Texas 75243 |
| Dermatology Treatment & Research Center, PA (DTRC) | Dallas, Texas 75230 |
| Menter Dermatology Research Institute | Dallas, Texas 75246 |
| Office of Mark S. Lee, MD | San Antonio, Texas 78229 |
| Progressive Clinical Research, PA | San Antonio, Texas 78229 |
| Office of Stephen Miller, MD, PA | San Antonio, Texas 78229 |
| Rockwood Research Center | Spokane, Washington 99202 |
| Rockwood Dermatology Center | Spokane, Washington 99202 |
| Wenatchee Valley Medical Center - Clinical Research Department | Wenatchee, Washington 98801 |
| Mountain State Clinical Research | Clarksburg, West Virginia 26301 |
| Madison Skin and Research, Inc. | Madison, Wisconsin 53719 |
