Phase 3, Randomized, Open-Label Study Of The Efficacy And Safety Of Crizotinib Versus Pemetrexed/Cisplatin Or Pemetrexed/Carboplatin In Previously Untreated Patients With Non-Squamous Carcinoma Of The Lung Harboring A Translocation Or Inversion Event Involving The Anaplastic Lymphoma Kinase (ALK) Gene Locus
Interventional
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Progression-Free Survival (PFS)
35 months
No
Pfizer CT.gov Call Center
Study Director
Pfizer
United States: Food and Drug Administration
A8081014
NCT01154140
January 2011
November 2013
Name | Location |
---|---|
Washington University School of Medicine | Saint Louis, Missouri 63110 |
Fox Chase Cancer Center | Philadelphia, Pennsylvania 19111 |
University of Washington Medical Center | Seattle, Washington 98195-6043 |
Barnes-Jewish Hospital | Saint Louis, Missouri 63110 |
Loma Linda University Medical Center | Loma Linda, California 92354 |
Ingalls Memorial Hospital | Harvey, Illinois 60426 |
North Shore University Hospital | Manhasset, New York 11030 |
Ochsner Clinic Foundation | New Orleans, Louisiana 70121 |
University of Wisconsin Hospital and Clinics | Madison, Wisconsin 53792-0001 |
Long Island Jewish Medical Center | New Hyde Park, New York 11040 |
Indiana University Melvin and Bren Simon Cancer Center | Indianapolis, Indiana 46202-5289 |
University of New Mexico Cancer Center | Albuquerque, New Mexico 87131-5636 |
University of Texas Southwestern Medical Center at Dallas | Dallas, Texas 75235-8897 |
Georgia Cancer Specialists | Decatur, Georgia 30033 |
Seattle Cancer Care Alliance | Seattle, Washington 98109 |
OHSU Knight Cancer Institute | Portland, Oregon 97239 |
Siteman Cancer Center | Saint Louis, Missouri 63110 |
Monroe Medical Associates | Chicago, Illinois 60603 |
Tower Hematology Oncology Medical Group | Los Angeles, California 90048 |
SUNY Upstate Medical University | Syracuse, New York 13210 |
Tower Cancer Research Foundation | Beverly Hills, California 90211 |
Dartmouth Hitchcock Medical Center | Lebanon, New Hampshire 03756 |
University of Chicago | Chicago, Illinois 60637 |
University of Texas MD Anderson Cancer Center | Houston, Texas 77030 |
Oregon Health and Science University | Portland, Oregon 97201 |
Georgetown University Hospital | Washington, District of Columbia 20007 |
Karmanos Cancer Institute | Detroit, Michigan 48201 |
Florida Hospital | Orlando, Florida 32803 |
The Emory Clinic | Atlanta, Georgia 30322 |
The Community Hospital | Munster, Indiana 46321 |
Wishard Health Services | Indianapolis, Indiana 46202-2859 |
Maine Center for Cancer Medicine | Scarborough, Maine 04074 |
Emory University Hospital | Atlanta, Georgia 30322 |
Tennessee Oncology, PLLC | Clarksville, Tennessee 37043 |
Hematology-Oncology Associates of Northern New Jersey | Morristown, New Jersey 07962 |
Sarah Cannon Research Institute | Nashville, Tennessee 37203 |
Methodist Hospital | Indianapolis, Indiana 46202 |
Indiana University Hospital | Indianapolis, Indiana 46202 |
Winship Cancer Institute - Emory University | Atlanta, Georgia 30322 |
Pharma Resource | East Providence, Rhode Island 02915 |
Memorial Medical Center | Las Cruces, New Mexico 88011 |
Cancer Institute Of Florida | Orlando, Florida 32804 |
Beth Israel Deaconess Medical Center (BIDMC) | Boston, Massachusetts 02215 |
CCTAP | Anaheim, California 92807 |
Loma Linda University Medical Center Pharmacy | Loma Linda, California 92354 |
Loma Linda University Cancer Center-Schuman Pavilion | Loma Linda, California 92354 |
Records Management Only- Loma Linda Cancer Center | Loma Linda, California 92354 |
Kaiser Permanente Southern California | San Diego, California 92108 |
CTTAP | San Diego, California 92120 |
Drug Shipment Address and Pharmacist Designees: | Washington, District of Columbia 20007 |
Lynn Cancer Institute Center for Hematology Oncology | Boca Raton, Florida 33486 |
Hematology and Oncology Consultants, PA | Orlando, Florida 32804 |
Investigational Drug Services | Orlando, Florida 32804 |
Emory University Hospital Midtown | Atlanta, Georgia 30308 |
Ship Drug To: Al Fisher, Pharm D. | Harvey, Illinois 60426 |
Monroe Medical Association | Munster, Indiana 46321 |
Dana-Farber Cancer Institute (DFCI) | Boston, Massachusetts 02215 |
Brigham and Women's Hospital (BWH) | Boston, Massachusetts 02115 |
Karmanos Cancer Institute at Farmington Hills | Farmington Hills, Michigan 48334 |
Siteman Cancer Center - West County | Creve Coeur, Missouri 63141 |
UNM Eye Clinic | Albuquerque, New Mexico 87106 |
NSLIJ Health System/Monter Cancer Center | Lake Success, New York 11042 |
Department of Medicine MSG at SUNY HSC at Syracuse, Inc. | Oneida, New York 13421 |
Vincent Armenio | East Providence, Rhode Island 02914 |
Henry-Joyce Cancer Clinic | Nashville, Tennessee 37232-5536 |
Vanderbilt Oncology Pharmacy | Nashville, Tennessee 37232 |
University of Texas Southwestern University Hospital - St. Paul | Dallas, Texas 75232 |
University of Texas Southwestern University Hospital - Zale Lipshy | Dallas, Texas 75235 |