A Multicenter, Open-label, Randomized Trial to Evaluate the Anti-cancer Effects of Zoledronic Acid and Circulating Tumor Cell Measurements in Patients With HER2-negative Metastatic Breast Cancer Without Bone Metastasis
Interventional
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Progression free survival (PFS)
up to 18 months
No
Novartis Pharmaceuticals
Study Director
Novartis Pharmaceuticals
United States: Food and Drug Administration
CZOL446EUS147
NCT01129336
June 2010
August 2012
Name | Location |
---|---|
Highlands Oncology Group | Springdale, Arkansas 72764 |
Hematology Oncology Services of Arkansas | Little Rock, Arkansas 72205 |
Wilshire Oncology Medical Group | Glendora, California 91741 |
The West Clinic | Memphis, Tennessee 38120 |
Northwest Medical Specialties | Tacoma, Washington 98405 |
Cooper Cancer Center | Voorhees, New Jersey 08043 |
Space Coast Medical Associates | Cocoa Beach, Florida 32931 |
Cancer Center of Kansas | Wichita, Kansas 67214 |
Sarah Cannon Research Institute | Nashville, Tennessee 37203 |
Marion L. Shepard Cancer Center | Washington, North Carolina |
Arena Oncology Associates, PC | Great Neck, New York 11021 |
Clopton Clinic | Jonesboro, Arkansas 72401 |
Berks Hematology Oncology | West Reading, Pennsylvania 19611 |
South Texas Oncology and Hematology, PA South Texas Oncology (2) | San Antonio, Texas 78258 |
Florida Cancer Specialists DeptofFloridaCancerSpecialists | Fort Myers, Florida 33901 |
Park Nicollet Institute Dept. of Park Nicollet | St. Louis Park, Minnesota 55416 |
Kootenai Medical Center Kootenai Medical Center | Coeur d'Alene, Idaho 83814 |
Hematology Oncology Center, Inc. | Elyria, Ohio 44035 |
Abington Hematology Oncology Associates, Inc | Willow Grove, Pennsylvania 19090 |
Southeast Nebraska Oncology Cancer Center | Lincoln, Nebraska 68510 |
Somerset Hematology Oncology Associates Somerset Hema Oncol Assoc (2) | Somerset, New Jersey 08873 |
Kaiser Permanente Medical Group Kaiser Permanente - Hawaii | Anaheim, California 92807 |
Loma Linda University Loma Linda Cancer Center | Loma Linda, California 92354 |
Hematology and Medical Oncology | Waterbury, Connecticut 06708 |
Lakeland Regional Cancer Center Dept. of Lakeland Regional | Lakeland, Florida 33803 |
Oncology Specialists, SC Lutheran General Cancer Instit | Park Ridge, Illinois 60068-0736 |
St. John's Mercy Medical Center St. John's Mercy Med Ctr | St. Louis, Missouri 63141 |
Hematology Oncology Centers of the Northern Rockies Hema Onc Ctr N. Rockies (4 | Billings, Montana 59101 |
Reno Oncology Consultants | Reno, Nevada 89502 |
Piedmont Hematology and Oncology Associates Piedmont Hem/Onc Assoc (2) | Winston-Salem, North Carolina 27103 |
Milton S Hershey Medical Center Hershey Medical Center (4) | Hershey, Pennsylvania 17033 |
East Texas Medical Center Cancer Institute Tyler Hem/Onc (3) | Tyler, Texas 75701 |
Medical Oncology & Hematology Associates of Northern VA Med. Onc&Hem Assoc. of No.VA | Reston, Virginia 20190 |