Weight Loss to Reduce Breast Cancer Risk Factors

Trial Information

Weight Loss to Reduce Breast Cancer Risk Factors

In sum, excess body weight and inactivity have emerged as strong avoidable causes of
postmenopausal breast cancer, with the greatest potential for primary prevention occurring
during the premenopausal years. However, surprisingly, no study to date has examined the
effects of a standard behavioral weight loss intervention on breast cancer risk markers in
premenopausal women. Understanding the effects of weight loss in premenopausal women is a
critical next step in existing research and will inform the development of future breast
cancer primary prevention programs. The purpose of this study is to determine the
feasibility of recruiting, treating, and retaining 20 overweight/obese women in a 12-week
randomized control trial examining feasibility and effects of a behavioral weight loss
program on breast cancer risk markers in premenopausal women. Participants will be randomly
assigned to either a 12-week comprehensive behavioral weight loss program (n=10) or control
condition (n=10). All women will be assessed at baseline and after 3 months of treatment.