Trial Information

Extended Interval Port Flushes: A Phase II Clinical Trial

This is a phase II, non-blinded, non-inferiority prospective cohort trial of patients with
ports (PAC) after a systemic therapy to evaluate the safety and effectiveness of PAC flushes
in 3 months intervals. Patients with any type of cancer are eligible. The study will extend
1 year from enrollment of the last patient. Each enrolled patient will have his or her port
flushed five times in 3 month intervals.

Patients will be enrolled after the completion of systemic therapy and after completion of
the restaging follow up, which is the time period from 4 weeks to 3 months after
discontinuation of the chemotherapy. Once patients are enrolled to extended interval PAC
flushes, they will be followed for one year. At the end of the year patients will return to
standard PAC flushes. If patients experience any PAC malfunction, it would be considered a
PAC failure and the flushing will reverted back to the schedule recommended by the
manufacturer.