Phase II Study of RAD001 and Bevacizumab in Recurrent Ovarian, Peritoneal, and Fallopian Tube Cancer An Investigator-initiated, Single-institution Trial at Magee-Womens Hospital
In this trial, approximately 50 patients will receive the study drug, RAD001 in combination
with bevacizumab (Avastin)chemotherapy. RAD001 will be taken orally once daily and
bevacizumab will be administered intravenously once every 14 days. In addition to study
treatment, a few blood samples and a sample of the patients tumor from a previous surgery if
available will be collected for research.
Interventional
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
To evaluate the progression-free survival at 6 months for RAD001 and bevacizumab in recurrent ovarian, peritoneal, and fallopian tube cancer
6 months to 1 year
Yes
Robert Edwards, MD
Principal Investigator
University of Pittsburgh, Magee-Womens Hospital, Gynecologic Oncology Division
United States: Food and Drug Administration
09-01-RAD001BEV
NCT01031381
September 2010
September 2013
Name | Location |
---|---|
Magee-Womens Hospital of UPMC | Pittsburgh, Pennsylvania 15213 |