The TEAM Trial (Tasigna Efficacy in Advanced Melanoma): A Phase II, Open Label, Multi-center, Single-arm Study to Assess the Efficacy of Tasigna ® in the Treatment of Patients With Metastatic and/or Inoperable Melanoma Harboring a c-Kit Mutation
Interventional
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention
Clinical efficacy of nilotinib based on overall response rate (ORR)
study period
No
Novartis Pharmaceuticals
Study Director
Novartis Pharmaceuticals
United States: Food and Drug Administration
CAMN107B2301
NCT01028222
June 2010
March 2013
Name | Location |
---|---|
Memorial Sloan Kettering Cancer Center | New York, New York 10021 |
Sidney Kimmel Comprehensive Cancer Center/Johns Hopkins Med. Medical Oncology | Baltimore, Maryland 21231 |
University of Pittsburgh Cancer Institute Dept of Hillman Cancer Center | Pittsburgh, Pennsylvania 15232 |
UCLA/ University of California Los Angeles UCLA | Los Angeles, California 90095 |
California Pacific Medical Center California Pacific Med | San Francisco, California 94120-7999 |
St. Luke's Hospital and Health Network St. Luke's Cancer Network (2) | Bethlehem, Pennsylvania |
Rush University Medical Center SC | Chicago, Illinois 60612 |
Dana Farber Cancer Institute DFCI - Brookline | Boston, Massachusetts 02115 |
Nevada Cancer Institute NVCC - Huntsman | Las Vegas, Nevada 89135 |
Wake Forest University Baptist Medical Center Dept. of Industry Research (2) | Winston-Salem, North Carolina 27157 |
City of Hope National Medical Center City of Hope national Med Ctr | Duarte, California 91010-3000 |
University of California San Diego UCSD Moores Cancer Center | La Jolla, California 92093-0658 |
University of California Irvine Dept of Hematology/Oncology | Orange, California 92868 |
University of California San Francisco UCSF Cancer & Leukima Group | San Francisco, California 94101 |
University of Colorado Univ Colorado 2 | Aurora, Colorado 80045 |
Florida Hematology & Oncology Specialists FLHCI | Orlando, Florida 32804 |
Oncology Specialists, SC Dept.of Oncology Specialists | Park Ridge, Illinois 60068-0736 |
Mayo Clinic - Rochester Mayo Clinic- Gonda | Rochester, Minnesota 55905 |
Washington University School of Medicine Camn107B2301 | St. Louis, Missouri 63110 |
Case Western Reserve Case Western | Cleveland, Ohio 44106-5000 |
Ohio State Comprehensive Cancer Center/James Cancer Hospital Ohio Univ/James Cancer Hosp | Columbus, Ohio 43210 |
Vanderbilt University Medical Center SC Vanderbilt | Nashville, Tennessee 37232 |
Baylor College of Medicine Baylor 2 | Dallas, Texas 75246 |
University of Texas Southwestern Medical Center Univ of Texas Southwestern Med | Dallas, Texas 75390-8527 |
Huntsman Cancer Institute Univ. of Utah HCI | Salt Lake City, Utah 84112-0550 |