A Multicenter, Randomized, Double Blind, Placebo Controlled Phase III Study of Panobinostat in Combination With Bortezomib and Dexamethasone in Patients With Relapsed Multiple Myeloma
Interventional
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
To compare progression-free survival in patients treated with panobinostat in combination with bortezomib and dexamethasone vs. patients treated by placebo in combination with bortezomib and dexamethasone.
30 months
No
Novartis Pharmaceuticals
Study Director
Novartis Pharmaceuticals
United States: Food and Drug Administration
CLBH589D2308
NCT01023308
December 2009
March 2014
Name | Location |
---|---|
Duke University Medical Center | Durham, North Carolina 27710 |
Dana Farber Cancer Institute | Boston, Massachusetts 02115 |
Kaiser Permanente | Sacramento, California |
Dayton CCOP | Dayton, Ohio 45429 |
Associates in Oncology/Hematology, P.C. | Kensington, Maryland 20895 |
Sarah Cannon Research Institute | Nashville, Tennessee 37203 |
Emory University School of Medicine/Winship Cancer Institute | Atlanta, Georgia 30322 |
Northeast Georgia Cancer Care | Athens, Georgia 30607 |
Bay Area Cancer Research | Concord, California 94520 |
LSU HEALTH SCIENCES CENTER/ LSU SCHOOL OF MEDICINE Feist-Weiller Cancer Center | New Orleans, Louisiana 70115 |
Quincy Medical Group | Quincy, Illinois 62301 |
Hubert H. Humphrey Cancer Center - Coon Rapids | Coon Rapids, Minnesota 55433 |
Pharma Resource | East Providence, Rhode Island 02915 |
Medical Specialist of Palm Beaches | Lake Worth, Florida 33467 |
Loyola University Chicago | Maywood, Illinois 60153 |
Western Pennsylvania Cancer Institute /Western Penn Hospital Western Pann. Cancer Inst. | Pittsburgh, Pennsylvania 15224 |
West Virginia University/ Mary Babb Randolph Cancer Center | Morgantown, West Virginia 26506 |
Legacy Pharma Research | Bismarck, North Dakota 58501 |
Missouri Cancer Associates Dept.ofMissouriCancerAssoc. | Columbia, Missouri 65201 |
Cancer Center of the High Plains | Amarillo, Texas 79106 |
Arizona Oncology Associates Tucson (Carondelet & Wilmot) | Phoenix, Arizona |
Rau, Subramanyam | Anaheim, California 92801 |
Southern California Permanente Medical Group SC | Los Angeles, California 90027 |
Stanford University Medical Center School of Medicine | Stanford, California 94304 |
Innovative Medical Research of South Florida Dept.ofInnovativeMedResearch | Miami Shores, Florida 33138 |
NorthWest Georgia Oncology Centers NW Georgia Oncology Centers PC | Marietta, Georgia 30060 |
St. Agnes Hospital Healthcare Cancer Center | Baltimore, Maryland 21229 |
Newland Medical Associates, PC Newland Medical - Southfield | Southfield, Michigan |
Minnesota Oncology Hematology, P.A. Minnesota Oncology Hematology, | Minneapolis, Minnesota 55404 |
East Orange VA Medical Center SC | East Orange, New Jersey 07018-1095 |
Mount Kisco Medical Group | Mt. Kisco, New York 10549 |
Signal Point Hematology Oncology, Inc. | Middletown, Ohio 45042 |
Vanderbilt Univeristy SC | Nashville, Tennessee 37232 |
MD Anderson Cancer Center/University of Texas MD Anderson CC | Houston, Texas 77030 |
Columbia Basin Hematology SC | Kennewick, Washington 99336 |
Swedish Cancer Institute SC | Seattle, Washington 98104 |
St. Mary Medical Center | Walla Walla, Washington 33962 |
Kaiser Permanente - California Southern Kaiser Permanente SCPMG | San Diego, California |
Boca Raton Community Hospital SC | Boca Raton, Florida 33486 |