Vibration Response Imaging (VRI) in Patients Who Are Potential Candidates for Surgical Resection
Primarily, VRI will be compared to perfusion (Q) scan by predicted post-operative (ppo) FEV1
and DLCO as predicted by VRI versus as predicted by Q scan. Secondary, the ppo as predicted
by each test will be compared with the actual FEV1 and DLCO at 3 months post-operative; If
these two methods provide similar results, VRI will be deemed an acceptable alternative to Q
scan for determining patient selection for lung resection. Finally, the patient outcomes (30
day mortality and pulmonary complications) for those patients falling within guideline
parameters using the VRI measurement will be analyzed to see if using VRI in clinical
practice would indeed allow prediction of satisfactory results (similar to literature
benchmarks).
Observational
Observational Model: Cohort, Time Perspective: Prospective
Comparison of ppo FEV1 and ppo DLCO as predicted by VRI with the values as predicted by Q scan
Prior to surgery
No
Frank C Detterbeck, MD
Principal Investigator
Yale University Medical School
United States: Institutional Review Board
DB041
NCT00966511
June 2009
December 2011
Name | Location |
---|---|
Emory University | Atlanta, Georgia 30322 |
Yale University School Of Medicine | New Haven, Connecticut 06520 |
Mt. Sinai School of Medicine | New York, New York 10029 |
The University of Texas MD Anderson Cancer Center | Houston, Texas 77030-4009 |
Boston Medical Center, Boston University | Boston, Massachusetts 02118 |
New York-Presbyterian Hospital/Columbia University Medical Center | New York, New York 10032 |