A Pilot Study of Flumist, a Live Attenuated Intranasal Influenza Vaccine, and Inactivated Influenza Vaccine in Children With Cancer
The secondary objectives of this study are to:
1. Describe the safety of FluMist and inactivated influenza vaccine.
2. Describe the incidence and duration of viral replication following immunization with
FluMist.
3. To examine the association between immunization response (seroconversion or
seroprotection) and baseline clinical factors (age, type of malignancy, absolute
neutrophil count, absolute lymphocyte count, serum IgA, IgG and IgM levels).
Interventional
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label
The primary objective of this study is to describe the immune response of FluMist compared with inactivated influenza vaccine in mild to moderately immunocompromised children with cancer
6 months
Yes
Silvana Carr, MD
Principal Investigator
St. Jude Children's Research Hospital
United States: Institutional Review Board
FMRESP
NCT00906750
October 2008
July 2011
Name | Location |
---|---|
St. Jude Children's Research Hospital | Memphis, Tennessee 38105-2794 |