Ovarian Tissue Freezing For Fertility Preservation In Women Facing A Fertility Threatening Medical Diagnosis Or Treatment Regimen: A Study By The National Physicians Cooperative of the Oncofertility Consortium At Northwestern University

Inclusion Criteria:

- Woman between the age of 18-41 years who will undergo surgery, chemotherapy, drug
treatment and/or radiation for the treatment or prevention of a medical condition or
malignancy expected to result in permanent and complete loss of subsequent ovarian
function or have a medical condition or malignancy that requires removal of all or
part of one or both ovaries.

- Patients may have newly diagnosed or recurrent disease. Those who were not enrolled
at the time of initial diagnosis are eligible if they have not received therapy that
is viewed as likely to result in complete and permanent loss of ovarian function.

- For patients undergoing elective removal of an ovary for fertility preservation only,
have two ovaries.

- Patients who already have stored cryopreserved ovarian tissue in a frozen state prior
to undergoing cancer treatments (surgery, chemotherapy or radiation) will be eligible
for enrollment with informed consent.

- Signed an approved informed consent and authorization permitting the release of
personal health information. The patient and/or the patient's legally authorized
guardian must acknowledge in writing that consent for specimen collection has been
obtained, in accordance with institutional policies approved by the U.S. Department
of Health and Human Services.

Exclusion Criteria:

- Women with psychological, psychiatric, or other conditions which prevent giving fully
informed consent.

- Women whose underlying medical condition significantly increases their risk of
complications from anesthesia and surgery.