A Children's Oncology Group Protocol for Collecting and Banking Osteosarcoma Specimens
N/A
N/A
N/A
N/A
N/A
Open (Enrolling)
Both
Sarcoma
Both
Sarcoma
Trial Information
A Children's Oncology Group Protocol for Collecting and Banking Osteosarcoma Specimens
OBJECTIVES:
- To collect biological specimens from patients with osteosarcoma at Children's Oncology
Group (COG) institutions.
- To provide a repository for long-term storage of osteosarcoma-related biological
materials.
- To make these specimens available to qualified researchers to understand the biology of
osteosarcoma and correlate these results with the patients' clinical data.
OUTLINE: After the initial submission of blood samples, patients may undergo open or closed
biopsy in order to obtain fresh and frozen tissue samples as well as paraffin embedded
material. Patients who are enrolled at the time of initial diagnosis but then have a
definitive surgery or develop recurrent disease may submit additional samples (paraffin
block, frozen and fresh tumor tissue, or slides together with blood samples). Autopsy tumor
samples may also be submitted.
Inclusion Criteria
DISEASE CHARACTERISTICS:
- All osteosarcoma patients seen at COG institutions are eligible, including the
following:
- Newly diagnosed patients
- Patients with recurrent disease who were not enrolled at the time of diagnosis
- The following specimens from the initial biopsy (and/or definitive surgery if an
up-front resection is performed) are required:
- Paraffin embedded block OR 30 unstained slides
- Pretreatment blood consisting of 5 mL serum, 10 mL plasma, and 10 mL heparinized
whole blood
- Fresh and frozen tumor specimens
PATIENT CHARACTERISTICS:
- Not specified
PRIOR CONCURRENT THERAPY:
- Patients are not required to enter a therapeutic study to enroll on this study
Type of Study:
Observational
Study Design:
N/A
Outcome Measure:
Collect biological specimens from patients with osteosarcoma
Safety Issue:
No
Principal Investigator
Richard Gorlick, MD
Investigator Role:
Study Chair
Investigator Affiliation:
Children's Hospital at Montefiore
Authority:
Unspecified
Study ID:
CDR0000562538
NCT ID:
NCT00899275
Start Date:
February 2008
Completion Date:
Related Keywords:
- Sarcoma
- osteosarcoma
- Osteosarcoma
- Sarcoma
Name | Location |
|---|---|
| Roswell Park Cancer Institute | Buffalo, New York 14263 |
| Children's Hospital of Philadelphia | Philadelphia, Pennsylvania 19104 |
| Mayo Clinic Cancer Center | Rochester, Minnesota 55905 |
| University of Chicago Cancer Research Center | Chicago, Illinois 60637 |
| Barbara Ann Karmanos Cancer Institute | Detroit, Michigan 48201 |
| Hurley Medical Center | Flint, Michigan 48503 |
| Medical City Dallas Hospital | Dallas, Texas 75230 |
| University of Texas Health Science Center at San Antonio | San Antonio, Texas 78284-7811 |
| Presbyterian - St. Luke's Medical Center | Denver, Colorado 80218 |
| Van Elslander Cancer Center at St. John Hospital and Medical Center | Grosse Pointe Woods, Michigan 48236 |
| Bronson Methodist Hospital | Kalamazoo, Michigan 49007 |
| CCOP - MeritCare Hospital | Fargo, North Dakota 58122 |
| Sanford Cancer Center at Sanford USD Medical Center | Sioux Falls, South Dakota 57117-5039 |
| Vanderbilt-Ingram Cancer Center | Nashville, Tennessee 37232-6838 |
| Marshfield Clinic - Marshfield Center | Marshfield, Wisconsin 54449 |
| Newark Beth Israel Medical Center | Newark, New Jersey 07112 |
| Rush University Medical Center | Chicago, Illinois 60612-3824 |
| Holden Comprehensive Cancer Center at University of Iowa | Iowa City, Iowa 52242-1002 |
| Ellis Fischel Cancer Center at University of Missouri - Columbia | Columbia, Missouri 65203 |
| Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill | Chapel Hill, North Carolina 27599-7570 |
| CCOP - Scott and White Hospital | Temple, Texas 76508 |
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore, Maryland 21231-2410 |
| Cancer Research Center of Hawaii | Honolulu, Hawaii 96813 |
| Cleveland Clinic Taussig Cancer Center | Cleveland, Ohio 44195 |
| Brooke Army Medical Center | Fort Sam Houston, Texas 78234-6200 |
| Children's Hospital of Orange County | Orange, California 92668 |
| Children's National Medical Center | Washington, District of Columbia 20010-2970 |
| Children's Mercy Hospital | Kansas City, Missouri 64108 |
| St. Joseph's Hospital and Medical Center | Paterson, New Jersey 07503 |
| Children's Hospital and Regional Medical Center - Seattle | Seattle, Washington 98105 |
| Nemours Children's Clinic | Jacksonville, Florida 32207 |
| All Children's Hospital | St. Petersburg, Florida 33701 |
| Children's Memorial Hospital - Chicago | Chicago, Illinois 60614 |
| Saint Jude Midwest Affiliate | Peoria, Illinois 61637 |
| Cardinal Glennon Children's Hospital | Saint Louis, Missouri 63104 |
| Schneider Children's Hospital | New Hyde Park, New York 11042 |
| St. Christopher's Hospital for Children | Philadelphia, Pennsylvania 19134-1095 |
| Driscoll Children's Hospital | Corpus Christi, Texas 78466 |
| Cook Children's Medical Center - Fort Worth | Fort Worth, Texas 76104 |
| Inova Fairfax Hospital | Falls Church, Virginia 22042-3300 |
| Fletcher Allen Health Care - University Health Center Campus | Burlington, Vermont 05401 |
| Phoenix Children's Hospital | Phoenix, Arizona 85016-7710 |
| Southern California Permanente Medical Group | Downey, California 90242 |
| Children's Hospital Central California | Madera, California 93638-8762 |
| Kosair Children's Hospital | Louisville, Kentucky 40202-3830 |
| Brooklyn Hospital Center | Brooklyn, New York 11201 |
| Palmetto Health South Carolina Cancer Center | Columbia, South Carolina 29203 |
| East Tennessee Children's Hospital | Knoxville, Tennessee 37901 |
| Children's Hospital of the King's Daughters | Norfolk, Virginia 23507 |
| Midwest Children's Cancer Center at Children's Hospital of Wisconsin | Milwaukee, Wisconsin 53226 |
| Arkansas Cancer Research Center at University of Arkansas for Medical Sciences | Little Rock, Arkansas 72205 |
| Blumenthal Cancer Center at Carolinas Medical Center | Charlotte, North Carolina 28232-2861 |
| Carol G. Simon Cancer Center at Morristown Memorial Hospital | Morristown, New Jersey 07962 |
| Loma Linda University Cancer Institute at Loma Linda University Medical Center | Loma Linda, California 92354 |
| Jonathan Jaques Children's Cancer Center at Miller Children's Hospital | Long Beach, California 90801 |
| Kaiser Permanente Medical Center - Oakland | Sacramento, California 95825 |
| Yale Cancer Center | New Haven, Connecticut 06520-8028 |
| Lee Cancer Care of Lee Memorial Health System | Fort Myers, Florida 33901 |
| Broward General Medical Center Cancer Center | Ft. Lauderdale, Florida 33316 |
| Baptist-South Miami Regional Cancer Program | Miami, Florida 33176 |
| Nemours Children's Clinic - Orlando | Orlando, Florida 32806 |
| Florida Hospital Cancer Institute at Florida Hospital Orlando | Orlando, Florida 32803-1273 |
| St. Joseph's Cancer Institute at St. Joseph's Hospital | Tampa, Florida 33607 |
| St. Vincent Indianapolis Hospital | Indianapolis, Indiana 46260 |
| Ochsner Cancer Institute at Ochsner Clinic Foundation | New Orleans, Louisiana 70121 |
| Alvin and Lois Lapidus Cancer Institute at Sinai Hospital | Baltimore, Maryland 21215 |
| Floating Hospital for Children at Tufts - New England Medical Center | Boston, Massachusetts 02111 |
| Breslin Cancer Center at Ingham Regional Medical Center | Lansing, Michigan 48910 |
| Hackensack University Medical Center Cancer Center | Hackensack, New Jersey 07601 |
| Albert Einstein Cancer Center at Albert Einstein College of Medicine | Bronx, New York 10461 |
| NYU Cancer Institute at New York University Medical Center | New York, New York 10016 |
| Mount Sinai Medical Center | New York, New York 10029 |
| Stony Brook University Cancer Center | Stony Brook, New York 11794-8174 |
| SUNY Upstate Medical University Hospital | Syracuse, New York 13210 |
| Mission Hospitals - Memorial Campus | Asheville, North Carolina 28801 |
| Presbyterian Cancer Center at Presbyterian Hospital | Charlotte, North Carolina 28233-3549 |
| Wake Forest University Comprehensive Cancer Center | Winston-Salem, North Carolina 27157-1096 |
| Rainbow Babies and Children's Hospital | Cleveland, Ohio 44106-5000 |
| Hollings Cancer Center at Medical University of South Carolina | Charleston, South Carolina 29425 |
| Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas | Dallas, Texas 75390 |
| Methodist Children's Hospital of South Texas | San Antonio, Texas 78229-3993 |
| Primary Children's Medical Center | Salt Lake City, Utah 84113-1100 |
| Providence Cancer Center at Sacred Heart Medical Center | Spokane, Washington 99220-2555 |
| Mary Babb Randolph Cancer Center at West Virginia University Hospitals | Morgantown, West Virginia 26506 |
| James P. Wilmot Cancer Center at University of Rochester Medical Center | Rochester, New York 14642 |
| UNMC Eppley Cancer Center at the University of Nebraska Medical Center | Omaha, Nebraska 68198-7680 |
| Memorial Cancer Institute at Memorial Regional Hospital | Hollywood, Florida 33021 |
| Childrens Hospital Los Angeles | Los Angeles, California 90027 |
| Children's Hospital and Research Center Oakland | Oakland, California 94609 |
| Lucile Packard Children's Hospital at Stanford University Medical Center | Palo Alto, California 95798 |
| Rady Children's Hospital - San Diego | San Diego, California 92123-4282 |
| UCSF Helen Diller Family Comprehensive Cancer Center | San Francisco, California 94115 |
| Alfred I. duPont Hospital for Children | Wilmington, Delaware 19803 |
| Lombardi Comprehensive Cancer Center at Georgetown University Medical Center | Washington, District of Columbia 20007 |
| M.D. Anderson Cancer Center at Orlando | Orlando, Florida 32806 |
| AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston Campus | Atlanta, Georgia 30322 |
| Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center | Savannah, Georgia 31403-3089 |
| Mountain States Tumor Institute at St. Luke's Regional Medical Center | Boise, Idaho 83712-6297 |
| University of Illinois Cancer Center | Chicago, Illinois 60612-7243 |
| Keyser Family Cancer Center at Advocate Hope Children's Hospital | Oak Lawn, Illinois 60453 |
| Simmons Cooper Cancer Institute | Springfield, Illinois 62794-9677 |
| Lucille P. Markey Cancer Center at University of Kentucky | Lexington, Kentucky 40536-0093 |
| Tulane Cancer Center Office of Clinical Research | Alexandria, Louisiana 71315-3198 |
| CancerCare of Maine at Eastern Maine Medical Center | Bangor, Maine 04401 |
| Dana-Farber/Harvard Cancer Center at Dana-Farber Cancer Institute | Boston, Massachusetts 02115 |
| C.S. Mott Children's Hospital at University of Michigan Medical Center | Ann Arbor, Michigan 48109-0286 |
| Masonic Cancer Center at University of Minnesota | Minneapolis, Minnesota 55455 |
| University of Mississippi Cancer Clinic | Jackson, Mississippi 39216-4505 |
| Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis | St. Louis, Missouri 63110 |
| Children's Hospital | Omaha, Nebraska 68114-4113 |
| CCOP - Nevada Cancer Research Foundation | Las Vegas, Nevada 89109-2306 |
| Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School | New Brunswick, New Jersey 08903 |
| University of New Mexico Cancer Center | Albuquerque, New Mexico 87131-5636 |
| Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center | New York, New York 10032 |
| Akron Children's Hospital | Akron, Ohio 44308-1062 |
| Nationwide Children's Hospital | Columbus, Ohio 43205-2696 |
| Dayton Children's - Dayton | Dayton, Ohio 45404-1815 |
| Oklahoma University Cancer Institute | Oklahoma City, Oklahoma 73104 |
| Knight Cancer Institute at Oregon Health and Science University | Portland, Oregon 97239-3098 |
| Penn State Children's Hospital | Hershey, Pennsylvania 17033-0850 |
| Children's Hospital of Pittsburgh of UPMC | Pittsburgh, Pennsylvania 15213 |
| Dell Children's Medical Center of Central Texas | Austin, Texas 78723 |
| Carilion Medical Center for Children at Roanoke Community Hospital | Roanoke, Virginia 24014 |
| Madigan Army Medical Center - Tacoma | Tacoma, Washington 98431 |
| West Virginia University Health Sciences Center - Charleston | Charleston, West Virginia 25302 |
| Riley's Children Cancer Center at Riley Hospital for Children | Indianapolis, Indiana 46202-5225 |
| Massachusetts General Hospital | Boston, Massachusetts 02114-2617 |
| Duke Cancer Institute | Durham, North Carolina 27710 |
| T.C. Thompson Children's Hospital | Chattanooga, Tennessee 37403 |
| Connecticut Children's Medical Center | Hartford, Connecticut 06106 |
| Children's Hospital Colorado Center for Cancer and Blood Disorders | Aurora, Colorado 80045 |
| Nemours Children's Clinic - Pensacola | Pensacola, Florida 32504 |
| Helen DeVos Children's Hospital at Spectrum Health | Grand Rapids, Michigan 49503 |
| Legacy Emanuel Children's Hospital | Portland, Oregon 97227 |
| BI-LO Charities Children's Cancer Center | Greenville, South Carolina 29605 |
| Mattel Children's Hospital at UCLA | Los Angeles, California 90095 |
| Children's Hospital of Alabama at University of Alabama at Birmingham | Birmingham, Alabama 35233 |
