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Establishment of a Head and Neck Cancer Tissue/Specimen Bank


N/A
18 Years
N/A
Not Enrolling
Both
Head and Neck Cancer

Thank you

Trial Information

Establishment of a Head and Neck Cancer Tissue/Specimen Bank


OBJECTIVES:

- Establish a tissue/specimen bank of biologic specimens collected from patients with
proven or suspected head and neck cancer.

- Establish a database to link materials acquisition and pathologic and clinical
information on these patients.

- Correlate clinical-pathological findings on these patients with future scientific
studies using the patient database.

- Test new hypotheses as they emerge.

OUTLINE: This is a prospective, multicenter study.

Patients enrolled on active Radiation Therapy Oncology Group clinical trials undergo biopsy
or surgical resection of head and neck tumors or premalignant lesions at participating
institutions. Tissue and other specimens collected at the time of biopsy or surgery are
submitted to the Head and Neck Cancer Tissue/Specimen Bank which acts as a central
repository for processing, storing, and preserving patient specimens for translational
research. Tissue samples include paraffin-embedded blocks or fresh or frozen samples of
normal squamous mucosa, tumors, or premalignant lesions of the upper aerodigestive tract.
Other specimens for tissue banking include serum, plasma, and lymphocytes isolated from
peripheral blood, as well as samples of patient saliva. Cells obtained from tissue bank
specimens may also be used to establish cell lines for future research.

PROJECTED ACCRUAL: An unlimited number of specimens will be accrued for this study.

Inclusion Criteria


DISEASE CHARACTERISTICS:

- Confirmed or suspected head and neck cancer

- Primary site recurrence allowed

- Potentially eligible for or participating in an active Radiation Therapy Oncology
Group treatment clinical trial

PATIENT CHARACTERISTICS:

- Zubrod performance status 0-1

PRIOR CONCURRENT THERAPY:

- See Disease Characteristics

- Concurrent radiotherapy, drug therapy, biopsy, or surgery allowed

Type of Study:

Observational

Study Design:

N/A

Outcome Measure:

Establishment of a head and neck cancer tissue/specimen bank

Safety Issue:

No

Principal Investigator

Randal S. Weber, MD

Investigator Role:

Study Chair

Investigator Affiliation:

M.D. Anderson Cancer Center

Authority:

United States: Federal Government

Study ID:

CDR0000460036

NCT ID:

NCT00898300

Start Date:

September 2005

Completion Date:

Related Keywords:

  • Head and Neck Cancer
  • stage I squamous cell carcinoma of the hypopharynx
  • stage II squamous cell carcinoma of the hypopharynx
  • stage III squamous cell carcinoma of the hypopharynx
  • stage IV squamous cell carcinoma of the hypopharynx
  • stage I squamous cell carcinoma of the larynx
  • stage II squamous cell carcinoma of the larynx
  • stage III squamous cell carcinoma of the larynx
  • stage IV squamous cell carcinoma of the larynx
  • stage I verrucous carcinoma of the larynx
  • stage II verrucous carcinoma of the larynx
  • stage III verrucous carcinoma of the larynx
  • stage IV verrucous carcinoma of the larynx
  • stage I basal cell carcinoma of the lip
  • stage II basal cell carcinoma of the lip
  • stage III basal cell carcinoma of the lip
  • stage IV basal cell carcinoma of the lip
  • stage I mucoepidermoid carcinoma of the oral cavity
  • stage II mucoepidermoid carcinoma of the oral cavity
  • stage III mucoepidermoid carcinoma of the oral cavity
  • stage IV mucoepidermoid carcinoma of the oral cavity
  • stage I verrucous carcinoma of the oral cavity
  • stage II verrucous carcinoma of the oral cavity
  • stage III verrucous carcinoma of the oral cavity
  • stage IV verrucous carcinoma of the oral cavity
  • stage I adenoid cystic carcinoma of the oral cavity
  • stage II adenoid cystic carcinoma of the oral cavity
  • stage III adenoid cystic carcinoma of the oral cavity
  • stage IV adenoid cystic carcinoma of the oral cavity
  • stage I squamous cell carcinoma of the lip and oral cavity
  • stage II squamous cell carcinoma of the lip and oral cavity
  • stage III squamous cell carcinoma of the lip and oral cavity
  • stage IV squamous cell carcinoma of the lip and oral cavity
  • metastatic squamous neck cancer with occult primary
  • stage I lymphoepithelioma of the nasopharynx
  • stage II lymphoepithelioma of the nasopharynx
  • stage III lymphoepithelioma of the nasopharynx
  • stage IV lymphoepithelioma of the nasopharynx
  • stage I squamous cell carcinoma of the nasopharynx
  • stage II squamous cell carcinoma of the nasopharynx
  • stage III squamous cell carcinoma of the nasopharynx
  • stage IV squamous cell carcinoma of the nasopharynx
  • stage I lymphoepithelioma of the oropharynx
  • stage II lymphoepithelioma of the oropharynx
  • stage III lymphoepithelioma of the oropharynx
  • stage IV lymphoepithelioma of the oropharynx
  • stage I squamous cell carcinoma of the oropharynx
  • stage II squamous cell carcinoma of the oropharynx
  • stage III squamous cell carcinoma of the oropharynx
  • stage IV squamous cell carcinoma of the oropharynx
  • stage I esthesioneuroblastoma of the paranasal sinus and nasal cavity
  • stage II esthesioneuroblastoma of the paranasal sinus and nasal cavity
  • stage III esthesioneuroblastoma of the paranasal sinus and nasal cavity
  • stage IV esthesioneuroblastoma of the paranasal sinus and nasal cavity
  • stage I inverted papilloma of the paranasal sinus and nasal cavity
  • stage II inverted papilloma of the paranasal sinus and nasal cavity
  • stage III inverted papilloma of the paranasal sinus and nasal cavity
  • stage IV inverted papilloma of the paranasal sinus and nasal cavity
  • stage I midline lethal granuloma of the paranasal sinus and nasal cavity
  • stage II midline lethal granuloma of the paranasal sinus and nasal cavity
  • stage III midline lethal granuloma of the paranasal sinus and nasal cavity
  • stage IV midline lethal granuloma of the paranasal sinus and nasal cavity
  • stage I squamous cell carcinoma of the paranasal sinus and nasal cavity
  • stage II squamous cell carcinoma of the paranasal sinus and nasal cavity
  • stage III squamous cell carcinoma of the paranasal sinus and nasal cavity
  • stage IV squamous cell carcinoma of the paranasal sinus and nasal cavity
  • stage I salivary gland cancer
  • stage II salivary gland cancer
  • stage III salivary gland cancer
  • stage IV salivary gland cancer
  • recurrent squamous cell carcinoma of the hypopharynx
  • recurrent squamous cell carcinoma of the larynx
  • recurrent squamous cell carcinoma of the lip and oral cavity
  • recurrent squamous cell carcinoma of the nasopharynx
  • recurrent squamous cell carcinoma of the oropharynx
  • recurrent squamous cell carcinoma of the paranasal sinus and nasal cavity
  • recurrent adenoid cystic carcinoma of the oral cavity
  • recurrent basal cell carcinoma of the lip
  • recurrent esthesioneuroblastoma of the paranasal sinus and nasal cavity
  • recurrent inverted papilloma of the paranasal sinus and nasal cavity
  • recurrent lymphoepithelioma of the nasopharynx
  • recurrent lymphoepithelioma of the oropharynx
  • recurrent midline lethal granuloma of the paranasal sinus and nasal cavity
  • recurrent mucoepidermoid carcinoma of the oral cavity
  • recurrent salivary gland cancer
  • recurrent verrucous carcinoma of the larynx
  • recurrent verrucous carcinoma of the oral cavity
  • recurrent metastatic squamous neck cancer with occult primary
  • Head and Neck Neoplasms

Name

Location

Roswell Park Cancer Institute Buffalo, New York  14263
Mayo Clinic Cancer Center Rochester, Minnesota  55905
Barbara Ann Karmanos Cancer Institute Detroit, Michigan  48201
CCOP - Upstate Carolina Spartanburg, South Carolina  29303
CCOP - Kansas City Kansas City, Missouri  64131
Penrose Cancer Center at Penrose Hospital Colorado Springs, Colorado  80933
Bronson Methodist Hospital Kalamazoo, Michigan  49007
West Michigan Cancer Center Kalamazoo, Michigan  49007-3731
Borgess Medical Center Kalamazooaa, Michigan  49001
University of Wisconsin Paul P. Carbone Comprehensive Cancer Center Madison, Wisconsin  53792-6164
Medical College of Wisconsin Cancer Center Milwaukee, Wisconsin  53226
Methodist Medical Center of Illinois Peoria, Illinois  61636
Albert Einstein Cancer Center Philadelphia, Pennsylvania  19141
LDS Hospital Salt Lake City, Utah  84143
Rush University Medical Center Chicago, Illinois  60612-3824
Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center Lebanon, New Hampshire  03756-0002
CCOP - Columbia River Oncology Program Portland, Oregon  97225
Veterans Affairs Medical Center - Portland Portland, Oregon  97207
Utah Valley Regional Medical Center - Provo Provo, Utah  84604
Monmouth Medical Center Long Branch, New Jersey  07740-6395
University of California Davis Cancer Center Sacramento, California  95817
St. Vincent Mercy Medical Center Toledo, Ohio  43608
James Graham Brown Cancer Center at University of Louisville Louisville, Kentucky  40202
CCOP - Toledo Community Hospital Toledo, Ohio  43623-3456
Winship Cancer Institute of Emory University Atlanta, Georgia  30322
Presbyterian Cancer Center at Presbyterian Hospital Charlotte, North Carolina  28233-3549
Medical University of Ohio Cancer Center Toledo, Ohio  43614
Toledo Hospital Toledo, Ohio  43606
Saint Peter's University Hospital New Brunswick, New Jersey  08901-1780
Wayne Memorial Hospital, Incorporated Goldsboro, North Carolina  27534
American Fork Hospital American Fork, Utah  84003
Utah Cancer Specialists at UCS Cancer Center Salt Lake City, Utah  84106
M.D. Anderson Cancer Center at Orlando Orlando, Florida  32806
Mountain States Tumor Institute at St. Luke's Regional Medical Center Boise, Idaho  83712-6297
Advocate Lutheran General Cancer Care Center Park Ridge, Illinois  60068-1174
Beth Israel Medical Center - Petrie Division New York, New York  10003-3803
Oklahoma University Cancer Institute Oklahoma City, Oklahoma  73104
M. D. Anderson Cancer Center at University of Texas Houston, Texas  77030-4009
Methodist Estabrook Cancer Center Omaha, Nebraska  68114-4199
Fox Chase Cancer Center - Philadelphia Philadelphia, Pennsylvania  19111-2497
Ingalls Cancer Care Center at Ingalls Memorial Hospital Harvey, Illinois  60426
Hickman Cancer Center at Bixby Medical Center Adrian, Michigan  49221
Community Cancer Center of Monroe Monroe, Michigan  48162
Kingsbury Center for Cancer Care at Cheshire Medical Center Keene, New Hampshire  03431
Wayne Radiation Oncology Goldsboro, North Carolina  27534
Wood County Oncology Center Bowling Green, Ohio  43402
Lima Memorial Hospital Lima, Ohio  45804
St. Luke's Hospital Maumee, Ohio  43537
Northwest Ohio Oncology Center Maumee, Ohio  43537
Toledo Clinic - Oregon Oregon, Ohio  43616
St. Charles Mercy Hospital Oregon, Ohio  43616
North Coast Cancer Care, Incorporated Sandusky, Ohio  44870
Mercy Hospital of Tiffin Tiffin, Ohio  44883
Toledo Clinic, Incorporated - Main Clinic Toledo, Ohio  43623
Fulton County Health Center Wauseon, Ohio  43567
Providence Milwaukie Hospital Milwaukie, Oregon  97222
Providence Cancer Center at Providence Portland Medical Center Portland, Oregon  97213-2967
Providence St. Vincent Medical Center Portland, Oregon  97225
Dixie Regional Medical Center - East Campus Saint George, Utah  84770
Southwest Washington Medical Center Cancer Center Vancouver, Washington  98668
Cancer Center at Ball Memorial Hospital Muncie, Indiana  47303
UAB Comprehensive Cancer Center Birmingham, Alabama  35294
Menorah Medical Center Overland Park, Kansas  66209
Shawnee Mission Medical Center Shawnee Mission, Kansas  66204
Haematology-Oncology Associates of Ohio and Michigan, PC Lambertville, Michigan  48144
Mercy Memorial Hospital - Monroe Monroe, Michigan  48162
Truman Medical Center - Hospital Hill Kansas City, Missouri  64108
St. Joseph Medical Center Kansas City, Missouri  64114
North Kansas City Hospital Kansas City, Missouri  64116
Saint Luke's Cancer Institute at Saint Luke's Hospital Kansas City, Missouri  64111
Research Medical Center Kansas City, Missouri  64132
Heartland Regional Medical Center Saint Joseph, Missouri  64506
North Coast Cancer Care - Clyde Clyde, Ohio  43410
Hematology Oncology Center Elyria, Ohio  44035
Fisher-Titus Medical Center Norwalk, Ohio  44857
Flower Hospital Cancer Center Sylvania, Ohio  43560
St. Anne Mercy Hospital Toledo, Ohio  43623
Adventist Medical Center Portland, Oregon  97216
Sandra L. Maxwell Cancer Center Cedar City, Utah  84720
Jon and Karen Huntsman Cancer Center at Intermountain Medical Center Murray, Utah  84157
Val and Ann Browning Cancer Center at McKay-Dee Hospital Center Ogden, Utah  84403
Fredericksburg Oncology, Incorporated Fredericksburg, Virginia  22401
John H. Stroger, Jr. Hospital of Cook County Chicago, Illinois  60612-9985
Good Samaritan Cancer Center at Good Samaritan Hospital Kearney, Nebraska  68848-1990
Rutherford Hospital Rutherfordton, North Carolina  28139
Gibbs Regional Cancer Center at Spartanburg Regional Medical Center Spartanburg, South Carolina  29303
Cancer Institute at St. John's Hospital Springfield, Illinois  62701
Boston University Cancer Research Center Boston, Massachusetts  02118
Parvin Radiation Oncology Kansas City, Missouri  64116
AnMed Cancer Center Anderson, South Carolina  29621
Georgia Cancer Center for Excellence at Grady Memorial Hospital Atlanta, Georgia  30303
Emory Crawford Long Hospital Atlanta, Georgia  30308
Saint John's Cancer Center at Saint John's Medical Center Anderson, Indiana  46016
Renown Institute for Cancer at Renown Regional Medical Center Reno, Nevada  89502
Norris Cotton Cancer Center - North Saint Johnsbury, Vermont  05819
Good Samaritan Cancer Care Center at Advocate Good Samaritan Hospital Downers Grove, Illinois  60515-1500
St. Vincent Oncology Center Indianapolis, Indiana  46260