4D PET/CT Imaging in Lung and Colorectal Cancer With Liver Metastasis
18 Years
N/A
Both
Colorectal Cancer, Lung Cancer, Liver Cancer
Trial Information
4D PET/CT Imaging in Lung and Colorectal Cancer With Liver Metastasis
Routine PET/CT scans are taken while patients are breathing normally. The motions made by
breathing can reduce the image quality of the scan. Minimizing the effects of this motion
by taking the images and processing the scans differently may improve the image quality.
The PET/CT Scan:
If you agree to take part in this study, a small plastic box (weighing less than 1 ounce)
will be placed on your abdominal area before your routine PET/CT scan. This box is used to
track your breathing motion. This information will be used to help process the scan.
Your PET/CT scan will be performed as usual. During the scan, the researchers will focus on
your lower chest/upper abdomen (areas that experience breathing motion). Having to focus on
this area might extend the scan by up to 12 minutes.
Length of Study:
Your participation on this study will be complete when your scheduled PET/CT scan is
complete.
This is an investigational study. The imaging focused on your lower chest/upper abdomen
during the scan is investigational.
Up to 26 patients will take part in this study. All will be enrolled at M. D. Anderson.
Inclusion Criteria:
1. Patients with suspected colorectal cancer with nodules in the lung or liver (1-2 cm
in diameter) will be eligible for this study.
2. Patients with suspected lung cancer with nodules in the lung or liver (1-2 cm in
diameter) will be eligible for this study.
Exclusion Criteria:
1. Pediatric patients (younger than 18 years) will be excluded.
2. Patients that cannot tolerate being scanned for an additional 12 minutes with arms
above their head will be excluded.
Type of Study:
Interventional
Study Design:
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Outcome Measure:
Learn if adjusting the PET/CT scanner to allow for breathing motion can improve the quality of PET/CT images.
Outcome Time Frame:
2 Years
Safety Issue:
No
Principal Investigator
Osama R. Mawlawi, PhD
Investigator Role:
Principal Investigator
Investigator Affiliation:
UT MD Anderson Cancer Center
Authority:
United States: Institutional Review Board
Study ID:
2008-0853
NCT ID:
NCT00862680
Start Date:
March 2009
Completion Date:
Related Keywords:
- Colorectal Cancer
- Lung Cancer
- Liver Cancer
- Lung Colorectum
- Colorectal cancer
- Lung Cancer
- Liver Cancer
- Non-small cell lung cancer
- NSCLC
- 4D PET/CT Imaging
- Positron emission tomography/computed tomography
- PET/CT scan
- Breathing motion
- Colorectal Neoplasms
- Liver Neoplasms
- Lung Neoplasms
- Neoplasm Metastasis
Name | Location |
|---|---|
| UT MD Anderson Cancer Center | Houston, Texas 77030 |
