Hypofractionated Radiotherapy for Localized Prostate Cancer (With CyberKnife or With IMRT)

Inclusion Criteria:

- Eligible patients will have clinical stage T1c through T2b, initial
PSA level <10 and a biopsy Gleason score of 3+3 or 3+4 with fewer than 50% of biopsy cores
involved.

- Patients who have had any form of prior curative treatment (surgery, radiotherapy,
cryotherapy) will not be eligible. A prior course of hormone therapy of less than 3
months duration will be allowed.

- Adult men will be considered.

- No life expectancy restrictions will apply.

- Performance Status will not be considered.

- No requirements for organ or marrow function will be made

- Ability to understand and the willingness to sign a written informed consent
document.

Exclusion Criteria:- No prior prostate treatment will be allowed.

- The use of other concurrent Investigational Agents will not be allowed.

- No exclusion requirements due to co-morbid disease or incurrent illness.

- No requirements regarding history of allergic reactions.

- Pregnancy or nursing patients is not applicable (ie. patients are male).