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An Initiative for Molecular Profiling in Advanced Cancer Therapy (IMPACT) Trial. A Molecular Profile-Based Study in Patients With Advanced Cancer Treated in the Investigational Cancer Therapeutics Program


N/A
N/A
N/A
Open (Enrolling)
Both
Advanced Cancers

Thank you

Trial Information

An Initiative for Molecular Profiling in Advanced Cancer Therapy (IMPACT) Trial. A Molecular Profile-Based Study in Patients With Advanced Cancer Treated in the Investigational Cancer Therapeutics Program


The prognosis of patients with advanced metastatic malignancies is poor, and their median
survival, irrespective of diagnosis, is approximately 8.8 months (95% confidence interval,
7.4 to 10.9 months). In recent years there has been increased interest in novel agents.

Elucidating the molecular basis of advanced cancer will lead to the development of
potentially curative strategies for these diseases aimed at the specific molecular and
genetic aberrations characteristic of specific tumors.

This study is a molecular profiling analyses of the patients' stored samples and will not
involve more than minimal risk to the subjects. Subjects are at no more than minimal risk
because only leftover blood, tissue, and patient data will be used for this study, and all
patient data will be kept confidential.


Inclusion Criteria:



1) Any patient seen in the department of Investigational Cancer Therapeutics is eligible.
Patients who have blood or tissue samples collected must be registered on the tissue bank
protocol (LAB07-0817).

Exclusion:

N/A

Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Retrospective

Outcome Measure:

Establish a program for the molecular profiling of patients with advanced cancer.

Outcome Time Frame:

6 Years

Safety Issue:

No

Principal Investigator

Apostolia M. Tsimberidou, MD, PHD

Investigator Role:

Study Chair

Investigator Affiliation:

UT MD Anderson Cancer Center

Authority:

United States: Institutional Review Board

Study ID:

2007-0885

NCT ID:

NCT00851032

Start Date:

February 2009

Completion Date:

Related Keywords:

  • Advanced Cancers
  • Advanced Cancer
  • Initiative for Molecular Profiling in Advanced Cancer Therapy
  • IMPACT
  • Molecular Profile-Based Study
  • Investigational Cancer Therapeutics Program
  • Molecular profiling
  • Phase I Therapies
  • Tissue Bank
  • Neoplasms

Name

Location
UT MD Anderson Cancer Center Houston, Texas  77030