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Continuing Access To The Tyrosine Kinase Inhibitor Of VEGFR 2, AG-013736 (A406) For Patients Previously Receiving AG-013736 In Clinical Trials


N/A
N/A
N/A
Open (Enrolling)
Both
Solid Tumors

Thank you

Trial Information

Continuing Access To The Tyrosine Kinase Inhibitor Of VEGFR 2, AG-013736 (A406) For Patients Previously Receiving AG-013736 In Clinical Trials


Inclusion Criteria:



- Patients who were assigned to an axitinib containing treatment arm in a previous
clinical trial

- Patients who were receiving axitinib tablets at the time their previous trial ended

- Patients who have stable (SD) or responding disease (PR or CR) documented by the
appropriate radiological, clinical, or laboratory assessments within 12 weeks before
enrollment (Note: response criteria from the previous AG-013736 protocol should be
used to determine stable or responding disease).

- Patients who have progressive disease (PD) but have experienced "clinical benefit"
as defined in the study protocol

Exclusion Criteria:

- Patients may not participate in this trial if the conditions for continuing treatment
in the previous AG-013736 protocol are not met

Type of Study:

Interventional

Study Design:

Endpoint Classification: Safety Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Outcome Measure:

Safety, especially thyroid gland abnormalities will be assessed using regular measurements of thyroid stimulating hormone in blood.

Outcome Time Frame:

10 Oct 2010

Safety Issue:

No

Principal Investigator

Pfizer CT.gov Call Center

Investigator Role:

Study Director

Investigator Affiliation:

Pfizer

Authority:

United States: Food and Drug Administration

Study ID:

A4061008

NCT ID:

NCT00828919

Start Date:

March 2003

Completion Date:

December 2015

Related Keywords:

  • Solid Tumors
  • VEGFR inhibitor
  • angi-angiogenic
  • tyrosine kinase inhibitor

Name

Location

Pfizer Investigational Site Blendora, California  91740
Pfizer Investigational Site Detroit, Michigan  48201
Pfizer Investigational Site Cincinnait, Ohio  45236
Pfizer Investigational Site Springfield, Illinois  62701-1014
Pfizer Investigational Site Bronx, New York  10461
Pfizer Investigational Site Houston, Texas  77030
Pfizer Investigational Site Federal Way, Washington  98003
Pfizer Investigational Site Westminster, Maryland  21157
Pfizer Investigational Site Kingston, Pennsylvania  18704-5535
Pfizer Investigational Site Milwaukee, Wisconsin  53215