Inclusion Criteria:

- Microscopically or cytologically confirmed non-small cell lung cancer. Histology may
include large cell, squamous cell, undifferentiated, or bronchioalveolar carcinoma,
or adenocarcinoma, but no small cell or carcinoid.

- Inoperable stage III B or metastatic stage IV NSCLC

- Measurable (bidimensionally) indicator lesion(s) which have not been irradiated.

- No prior systemic chemotherapy. Prior irradiation for NSCLC is permitted, however,
the measurable or evaluable non-measurable disease must be completely outside the
radiation portal or there must be radiologic proof of progressive disease. If a
patient is receiving palliative radiation, other than the chest, to one site at 30
cGy or less, then the patient is eligible and chemotherapy can proceed immediately
after palliative RT.

- ECOG performance status 0 or 1 at screening and on the first day of treatment

- Life expectancy = 12 weeks.

- Patients must be > 4 weeks from prior radiation therapy to the pelvis, spine or long
bones, and must be recovered from all side effects.

- Patients must be > 3 weeks from prior major surgery, except for a simple biopsy or
placement of a venous access device.

Exclusion Criteria:

- No patient may have the following:

- Neutrophils < 1,500/mm3.

- Platelets < 100,000/mm3.

- Serum creatinine >1.8 mg/dL.

- SGOT > 1.5 times the upper limit of normal for institution.

- Total bilirubin > the upper limit of normal for institution.

- Alkaline phosphatase > 5 times the upper limit of normal for institution.

- Pregnant or lactating females or females of childbearing potential not employing
adequate contraception.

- History of other malignancy within the last five years which could affect the
diagnosis of NSCLC, except basal cell carcinoma of the skin or carcinoma in situ of
the cervix.

- Current metastatic CNS disease, if present, must have been treated and clinically
stable for at least 3 weeks prior to initial Taxotere treatment. Patients with
documented meningeal carcinomatosis are not eligible.

- Grade 2 or greater peripheral neuropathy.

- Psychological, familial, sociological or geographical conditions which do not permit
weekly medical follow-up and compliance with the study protocol.

- Patients who are medically unstable, including but not limited to active infection,
acute hepatitis, gastrointestinal bleeding, uncontrolled cardiac arrhythmias,
uncontrolled angina, uncontrolled hypercalcemia, uncompensated congestive heart
failure, uncontrolled diabetes, dementia, seizures, superior vena cava syndrome, and
patients whose circumstances do not permit completion of the study or the required
follow-up.

- Patients with a history of hypersensitivity reaction to products containing
Polysorbate 80 (Tween 80).

- Patients requiring concurrent treatment with corticosteroids unless chronic treatment
(> 6 months) at low doses (< 20 mg/day of methylprednisolone or equivalent).

- Patients receiving an investigational drug within 3 weeks of registration.

The above information is not intended to contain all considerations relevant to a
patient's potential participation in a clinical trial.