Altered Gene Expression in Colorectal "Smears" of Individuals With Colon Cancer
N/A
50 Years
N/A
50 Years
N/A
Open (Enrolling by invite only)
Both
Colorectal Cancer Screening
Both
Colorectal Cancer Screening
Trial Information
Altered Gene Expression in Colorectal "Smears" of Individuals With Colon Cancer
Inclusion Criteria:
- willing to provide informed consent
- greater than or equal to 50 years of age
- patient is scheduled for routine colonoscopy procedure or colorectal cancer surgery
- subject is willing to provide colorectal mucosal sample for gene expression testing
Exclusion Criteria:
- recent radiation or treatment for gynecologic, prostate or rectal cancer
- recent surgery for anal rectal disease
- polys, family or self history of cancer (control group only)
- GI disease
- any mucosal disease or systemic condition that may confound the scientific
interpretation of the gene expression results
Type of Study:
Observational
Study Design:
Observational Model: Case Control, Time Perspective: Prospective
Outcome Measure:
- To select a threshold for Mahalanobis distance to determine the best operating characteristics (sensitivity and specificity) in subjects with cancer and subjects without cancer. - To explore other empirical metrics based on previous exploratory data
Outcome Time Frame:
Mai 2009
Safety Issue:
No
Authority:
United States: Institutional Review Board
Study ID:
IGS-08-001
NCT ID:
NCT00720993
Start Date:
August 2008
Completion Date:
May 2009
Related Keywords:
- Colorectal Cancer Screening
- Colorectal cancer screening
- Gene expression
- RTPCR
- Colorectal Neoplasms
Name | Location |
|---|---|
| Mayo Clinic | Rochester, Minnesota 55905 |
