Inclusion Criteria:

- Subjects >= 18 years of age, requiring non-emergent, open, abdominal,
retroperitoneal, pelvic or thoracic (non-cardiac) surgical procedures

- Presence of an appropriate soft tissue Target Bleeding Site (TBS) as identified
intraoperatively by the surgeon

- Subjects must be willing to participate in the study, and provide written informed
consent

Exclusion Criteria:

- Subjects with any intra-operative findings identified by the surgeon that may
preclude conduct of the study procedure

- Subject with TBS within an actively infected field

- Bleeding site is in, around, or in proximity to foramina in bone, or areas of bony
confine

- Subjects with known intolerance to blood products or to one of the components of the
study product

- Subjects unwilling to receive blood products

- Subjects with immunodeficiency diseases (including known HIV)

- Subjects who are known, current alcohol and / or drug abusers

- Subjects who have participated in another investigational drug or device research
study within 30 days of enrollment

- Female subjects who are pregnant or nursing