A 24 Month, Multicenter, Open-label, Randomized, Controlled Study to Evaluate the Efficacy and Safety of Concentration-controlled Everolimus to Eliminate or to Reduce Tacrolimus Compared to Tacrolimus in de Novo Liver Transplant Recipients
Interventional
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Assessment of renal function by Estimated Glomerular Filtration Rate,eGFR , using abbreviated Modification of Diet in Renal Disease at 12-mths post-transplantation Composite efficacy failure of death,graft loss,or loss to follow-up at 12-mths post-trans.
12 months post-transplantation
No
Novartis
Study Director
Novartis
Italy: The Italian Medicines Agency
CRAD001H2304
NCT00622869
January 2008
Name | Location |
---|---|
Baylor College of Medicine | Houston, Texas 77030 |
UCSF | San Francisco, California 941430324 |
Washington University School of Medicine | Saint Louis, Missouri 63110 |
Medical University of South Carolina | Charleston, South Carolina 29425-0721 |
Cedars-Sinai Medical Center | Los Angeles, California 90048 |
Piedmont Hospital | Atlanta, Georgia 30309 |
Methodist Hospital | Houston, Texas 77030 |
University of North Carolina | Chapel Hill, North Carolina 27599 |
Duke University Medical Center | Durham, North Carolina 27710 |
Georgetown University | Washington, District of Columbia 20007-2197 |
Oregon Health Sciences University | Portland, Oregon |
Cleveland Clinic | Cleveland, Ohio 44195 |
University of Chicago Medical Center | Chicago, Illinois 60637 |
University of Texas Health Science Center | San Antonio, Texas 78284 |
Thomas Jefferson University | Philadelphia, Pennsylvania 19107-6541 |
UCLA | Los Angeles, California 90095 |
University of Kentucky | Lexington, Kentucky 40536-0098 |
New York University | New York, New York 10016 |
Hershey Medical Center | Hershey, Pennsylvania 17033 |
Integris Baptist Medical Center | Oklahoma City, Oklahoma 73112 |
Columbia University Medical Center | New York, New York 10032 |
Lahey Clinic Medical Center | Burlington, Massachusetts 01805 |
Memorial Hermann Hospital | Houston, Texas 77030 |
John Hopkins University | Baltimore, Maryland 21231 |
University of Southern CA | Los Angeles, California 90033 |
University of Colorado / Anchutz Cancer Pavilion | Aurora, Colorado 80045 |
Miami School of Medicine | Miami, Florida 33136 |
Lifelink, Inc | Tampa, Florida 33606 |
Willis Knighton - LSU HSC | Shreveport, Louisiana 71103 |
U of Maryland Medical Center | Baltimore, Maryland 21201 |
Henry Ford Hospital Transplant Institute | Detroit, Michigan 48202 |
University of Minnesota Research Services Org | Minneapolis, Minnesota 55414 |
Mayo Clinic Transplant Center | Rochester, Minnesota 55905 |
UMD, Division of Transplant Surgery | Newark, New Jersey 07101 |
Vanderbuilt Transplant Center | Nashville, Tennessee 37232 |
The Baylor College of Medicine | Dallas, Texas 75203 |
Methodist Dallas Liver Insititute | Dallas, Texas 75203 |