Inclusion Criteria:

- Biopsy proven NRSTS or bone sarcoma

- Less than or equal to 30 years of age

- Patients must have been treated with a standardly accepted chemotherapy regimen if
chemotherapy is indicated

- Patients must be willing to receive follow-up care for a minimum of five years after
treatment at MGH and annual visits unless it is too difficult to return to MGH for
follow-up care. In that event, the patient or guardian must be willing to have their
outside medical information released in order to track the results of treatment

- Timing of radiation may be according to concurrent protocol

Exclusion Criteria:

- Co-morbidities that would make the use of radiation too toxic to deliver safely, such
as serious local injury of collagen vascular disease

- Patients who are pregnant

- Previous treatment with radiation therapy

- Concurrent adriamycin or gemcitabine chemotherapy is planned, unless on a concurrent
protocol