High Dose Chemotherapy With Autologous Bone Marrow Transplantation in the Treatment of Metastatic Breast Cancer
18 Years
70 Years
Female
Breast Neoplasms
Trial Information
High Dose Chemotherapy With Autologous Bone Marrow Transplantation in the Treatment of Metastatic Breast Cancer
There are 2 phases to this study: 1) Induction- which consists of the administration of
chemotherapeutic drugs- at the end of this phase if the cancer has responded, bone marrow
will be collected and frozen untol ready for re-infusion; 2) 2nd phase- involves high-doses
of chemotherapy followed by infusion of bone marrow cells
Inclusion Criteria:
- Histologically confirmed diagnosis of breast cancer
- Age 18-70
- Breast cancer at first clinical evidence of metastatic disease
- Must have objectively measurable or evaluable disease or be in complete remission
Exclusion Criteria:
- Previous diagnosis of another invasive carcinaom within 10 years (except skin cancer)
- CNS involvement
Type of Study:
Interventional
Study Design:
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Outcome Measure:
Once 10 patients enrolled in the study ar followed for at least 6 months, a preliminary analysis of the data will occur.
Outcome Time Frame:
Undetermined
Safety Issue:
No
Principal Investigator
George Selby, MD
Investigator Role:
Principal Investigator
Investigator Affiliation:
University of Oklahoma
Authority:
United States: Institutional Review Board
Study ID:
OU 9206
NCT ID:
NCT00584428
Start Date:
June 1992
Completion Date:
March 2002
Related Keywords:
- Breast Neoplasms
- Breast Cancer
- Cancer Treatment
- Breast Cancer Treatment
- Breast Neoplasms
- Neoplasms
Name | Location |
|---|---|
| University of Oklahoma Health Sciences Center | Oklahoma City, Oklahoma 73104 |
