Effect of Lap-Band Induced Weight Loss on Serum PSA Levels, Testosterone, Estrogen and Other Serum Markers
20 Years
60 Years
Male
Obesity, Prostate Cancer
Trial Information
Effect of Lap-Band Induced Weight Loss on Serum PSA Levels, Testosterone, Estrogen and Other Serum Markers
The main objective of this study is to determine whether interpretation of PSA levels in
morbidly obese men require correction due to the obesity itself. Secondary outcome measures
that will be followed include the affect of obesity and weight loss on testosterone,
estradiol and leptin. In as much as these might also affect PSA, we will be measuring these
values as well. Also, we do not know the effects of lap-band induced weight loss on
clinical outcome measures of sexual, bowel and urinary function. Thus we will aim to
investigate these parameters as well.
Inclusion Criteria:
- obese men undergoing lap-band surgey
Exclusion Criteria:
- prior diagnosis of prostate cancer, prior prostate surgery, use of 5-alpha reductase
inhibitors and history prostatitsis or recurrent UTI.
Type of Study:
Observational
Study Design:
Observational Model: Case-Only, Time Perspective: Prospective
Outcome Measure:
PSA value
Outcome Time Frame:
18 months
Principal Investigator
Jason Wynberg, MD
Investigator Role:
Principal Investigator
Investigator Affiliation:
MMC
Authority:
United States: Institutional Review Board
Study ID:
07/09/VA18
NCT ID:
NCT00562341
Start Date:
November 2007
Completion Date:
December 2009
Related Keywords:
- Obesity
- Prostate Cancer
- obesity
- psa
- prostate cancer
- Obesity
- Prostatic Neoplasms
- Weight Loss
Name | Location |
|---|---|
| Maimonides Medical Center | Brooklyn, New York 11219 |
