Inclusion Criteria:

1. Primary treatment at MD Anderson for prostate cancer using: radical retropubic
prostatectomy, robotic prostatectomy, photon external beam radiation, photon external
beam radiation with hormone therapy, proton radiation, radioisotopic implant,
cryotherapy, or active surveillance.

2. Neoadjuvant, concurrent and adjuvant androgen ablation in conjunction with photon
external beam radiation is allowed if not greater than 6 months total duration.
Hormone therapy will be given as an LHRH agonist with or without an antiandrogen.

3. Pathologic diagnosis of prostate adenocarcinoma

4. AJCC (VI) stage T1-T3b N0M0

5. Ability to read, write, and fill out the self-survey questionnaires

6. Patients may be simultaneously enrolled on other MD Anderson treatment or laboratory
protocols. The EPIC Survey will be used for both this protocol and for protocol
2007-0209 such that patients enrolled on both protocols will complete only one
document at each survey point. Simultaneous enrollment on other survey protocols will
be handled in a similar manner.

Exclusion Criteria:

1. Histology other than adenocarcinoma

2. Stage T4, nodal or distant metastasis

3. Prior treatment for prostate cancer except for neoadjuvant, concurrent and adjuvant
androgen deprivation of 6 months or less duration in patients treated with photon
radiation. Hormone therapy in all other modalities is not allowed.

4. Chemotherapy or molecular targeting therapy as primary, neoadjuvant or adjuvant
treatment

5. Treatment for another pelvic malignancy, to include surgery or radiation

6. Treatment for another malignancy with chemotherapy completed within one year or less
of treatment for prostate cancer.

7. Inflammatory bowel disease (eg. Crohn's or Ulcerative Colitis)

8. Patients 18 years or younger.